66516-1-Ig

antibody from Proteintech Group

Targeting: SMAD3 HsT17436, JV15-2, MADH3

Provider product page for 66516-1-Ig

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Antibody data

Antibody Data
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Product number: 66516-1-Ig - Provider product page
Provider: Proteintech Group
Product name: SMAD3 antibody
Antibody type: Monoclonal
Description: SMAD3 antibody (Cat. #66516-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1F10B2
Vial size: 20ul, 150ul

SMAD3 protein structure - 66516-1-Ig shown in red.

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Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.

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Sun Q, Xu J, Yuan F, Liu Y, Chen Q, Guo L, Dong H, Liu B
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Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis.

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Elevated Angiotensin-II Levels Contribute to the Pathogenesis of Open-Angle Glaucoma Via Inducing the Expression of Fibrosis-Related Genes in Trabecular Meshwork Cells Through a ROS/NOX4/SMAD3 Axis.

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Hepatic stellate cell-released CXCL1 aggravates HCC malignant behaviors through the MIR4435-2HG/miR-506-3p/TGFB1 axis.

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DLK1 overexpression improves sepsis-induced cardiac dysfunction and fibrosis in mice through the TGF-β1/Smad3 signaling pathway and MMPs.

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Shi L, Wang Z, Rong J, Fei X, Li X, He B, Gong W, Qian J
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Exosomal ITGB6 from dormant lung adenocarcinoma cells activates cancer-associated fibroblasts by KLF10 positive feedback loop and the TGF-β pathway.

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The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis.

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Cell death & disease 2023 Dec 14;14(12):826

Fu M, Zhang J, Zhang L, Feng Y, Fang X, Zhang J, Wen W, Hua W, Mao Y
Cellular and molecular neurobiology 2023 Aug;43(6):2975-2987

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Ni WJ, Zhou H, Lu H, Ma NN, Hou BB, Li W, Kong FX, Yu JT, Hou R, Jin J, Wen JG, Zhang T, Meng XM
Clinical and translational medicine 2023 Aug;13(8):e1359

Adipose-derived mesenchymal stem cell therapy for reverse bleomycin-induced experimental pulmonary fibrosis.

Zhao X, Wu J, Yuan R, Li Y, Yang Q, Wu B, Zhai X, Wang J, Magalon J, Sabatier F, Daumas A, Zhu WM, Zhu N
Scientific reports 2023 Aug 14;13(1):13183

CCL17 drives fibroblast activation in the progression of pulmonary fibrosis by enhancing the TGF-β/Smad signaling.

Wang QR, Liu SS, Min JL, Yin M, Zhang Y, Zhang Y, Tang XN, Li X, Liu SS
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TIAR and FMRP shape pro-survival nascent proteome of leukemia cells in the bone marrow microenvironment.

Wolczyk M, Serwa R, Kominek A, Klejman A, Milek J, Chwałek M, Turos-Korgul L, Charzyńska A, Dabrowski M, Dziembowska M, Skorski T, Piwocka K, Podszywalow-Bartnicka P
iScience 2023 Apr 21;26(4):106543

Anti-fibrotic effect of extracellular vesicles derived from tea leaves in hepatic stellate cells and liver fibrosis mice.

Gong Q, Zeng Z, Jiang T, Bai X, Pu C, Hao Y, Guo Y
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Iodine-125 Seeds Inhibit Carcinogenesis of Hepatocellular Carcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via TGF-β1/Smad Signaling.

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Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.

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Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.

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Experimental eye research 2022 Apr;217:108971

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Bioorganic chemistry 2021 Sep;114:105222

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Experimental and therapeutic medicine 2021 Oct;22(4):1093

Study on the potential nephrotoxicity and mutagenicity of aristolochic acid IVa and its mechanism.

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Luo X, Deng Q, Xue Y, Zhang T, Wu Z, Peng H, Xuan L, Pan G
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)

Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.

Wang R, Zhang D, Tang D, Sun K, Peng J, Zhu W, Yin S, Wu Y
International immunopharmacology 2021 Jan;90:107151

miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.

Chen S, Luo Y, Cui L, Yang Q
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Quercetin ameliorates podocyte injury via inhibition of oxidative stress and the TGF-β1/Smad pathway in DN rats.

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Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.

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