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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2857 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2857, RRID:AB_1576916
- Product name
- LINGO1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of LINGO1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models.
TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
Inoue H, Lin L, Lee X, Shao Z, Mendes S, Snodgrass-Belt P, Sweigard H, Engber T, Pepinsky B, Yang L, Beal MF, Mi S, Isacson O
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 4;104(36):14430-5
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 4;104(36):14430-5
TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.
Satoh J, Tabunoki H, Yamamura T, Arima K, Konno H
Neuropathology and applied neurobiology 2007 Feb;33(1):99-107
Neuropathology and applied neurobiology 2007 Feb;33(1):99-107
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
Mosyak L, Wood A, Dwyer B, Buddha M, Johnson M, Aulabaugh A, Zhong X, Presman E, Benard S, Kelleher K, Wilhelm J, Stahl ML, Kriz R, Gao Y, Cao Z, Ling HP, Pangalos MN, Walsh FS, Somers WS
The Journal of biological chemistry 2006 Nov 24;281(47):36378-90
The Journal of biological chemistry 2006 Nov 24;281(47):36378-90
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of LINGO1 (arrow) using rabbit LINGO1 polyclonal antibody (Cat # PAB2857). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 polyclonal antibody (Cat # PAB2857) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
