Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- MAB3086 - Provider product page
- Provider
- R&D Systems
- Product name
- Human LINGO-1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human LINGO-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) LINGO-2 or rhLINGO-3 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
NP_116197
- Isotype
- IgG
- Antibody clone number
- 332233
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions.
Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.
Jepson S, Vought B, Gross CH, Gan L, Austen D, Frantz JD, Zwahlen J, Lowe D, Markland W, Krauss R
The Journal of biological chemistry 2012 Jun 22;287(26):22184-95
The Journal of biological chemistry 2012 Jun 22;287(26):22184-95
Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.
Raiker SJ, Lee H, Baldwin KT, Duan Y, Shrager P, Giger RJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Sep 15;30(37):12432-45
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Sep 15;30(37):12432-45
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