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- References [7]
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- Product number
- 12238-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12238-1-AP, RRID:AB_2142636
- Product name
- MKRN2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MKRN2 antibody (Cat. #12238-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MKRN2 enhances hepatocellular carcinoma proliferation through the p38 MAPK pathway.
MKRN2 attenuates LPS-induced apoptosis in lung epithelial cells via ubiquitination-mediated p53 degradation.
The RNA-binding E3 ligase MKRN2 selectively disrupts Il6 translation to restrain inflammation.
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53.
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells.
Chen X, Yan Z, Du X, Zhang Z, Liu X, Zhang J, Hu L, He K, Wang J, Han Y
Human cell 2026 Feb 25;39(3)
Human cell 2026 Feb 25;39(3)
MKRN2 attenuates LPS-induced apoptosis in lung epithelial cells via ubiquitination-mediated p53 degradation.
Ma R, Su H, Liu J
Biochemical and biophysical research communications 2025 Sep 25;781:152476
Biochemical and biophysical research communications 2025 Sep 25;781:152476
The RNA-binding E3 ligase MKRN2 selectively disrupts Il6 translation to restrain inflammation.
Yu Z, Li X, Huang J, Pan J, Cheng J, Liu P, Yang M, Chen T, Zhang Q, Zhou Y, Wu J, Han T, Li J, Xu Y, Wen M, Zhang X, Wang C, Cao X
Nature immunology 2025 Jul;26(7):1036-1047
Nature immunology 2025 Jul;26(7):1036-1047
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Wang J, Wang X, Chen F, Ning Q, Liu Y, Zhu Y, Wei W, Leng M, Wang Z, Jin P, Li Q
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53.
Yang Y, Luo Y, Huang S, Tao Y, Li C, Wang C
Cancer biomarkers : section A of Disease markers 2023;36(4):267-278
Cancer biomarkers : section A of Disease markers 2023;36(4):267-278
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
Zhang Y, Cui N, Zheng G
Oncology letters 2020 Mar;19(3):1975-1984
Oncology letters 2020 Mar;19(3):1975-1984
Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells.
Jia C, Tang H, Yang Y, Yuan S, Han T, Fang M, Huang S, Hu R, Li C, Geng W
Biochemical and biophysical research communications 2020 Aug 13;529(1):43-50
Biochemical and biophysical research communications 2020 Aug 13;529(1):43-50
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MKRN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MKRN2. This antibody recognizes human,mouse,rat antigen. The MKRN2 antibody has been validated for the following applications: ELISA, WB analysis.
