Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 13623-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13623-1-AP, RRID:AB_2303892
- Product name
- TRIM15 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRIM15 antibody (Cat. #13623-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis.
Whole-genome DNA methylation and DNA methylation-based biomarkers in lung squamous cell carcinoma.
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Tripartite motif-containing 15 overexpression in non-small cell lung cancer is associated with poor patient prognoses.
TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.
Cai H, Zhao J, Zhang Q, Wu H, Sun Y, Guo F, Zhou Y, Qin G, Xia W, Zhao Y, Liang X, Yin S, Qin Y, Li D, Wu H, Ren D
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167183
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167183
Whole-genome DNA methylation and DNA methylation-based biomarkers in lung squamous cell carcinoma.
Cai Q, He B, Tu G, Peng W, Shi S, Qian B, Liang Q, Peng S, Tao Y, Wang X
iScience 2023 Jul 21;26(7):107013
iScience 2023 Jul 21;26(7):107013
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
Yang C, Jin X, Liu X, Wu G, Yang W, Pang B, Jiang J, Liao D, Zhang Y
Cell death & disease 2023 Jan 20;14(1):47
Cell death & disease 2023 Jan 20;14(1):47
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Zhu G, Herlyn M, Yang X
Nature cell biology 2021 Sep;23(9):978-991
Nature cell biology 2021 Sep;23(9):978-991
Tripartite motif-containing 15 overexpression in non-small cell lung cancer is associated with poor patient prognoses.
Han X, Huang C, Qu X, Liu S, Yang X, Wang Y, Bie F, Liu Q, Du J
Journal of Cancer 2019;10(4):843-852
Journal of Cancer 2019;10(4):843-852
TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.
Uchil PD, Pawliczek T, Reynolds TD, Ding S, Hinz A, Munro JB, Huang F, Floyd RW, Yang H, Hamilton WL, Bewersdorf J, Xiong Y, Calderwood DA, Mothes W
Journal of cell science 2014 Sep 15;127(Pt 18):3928-42
Journal of cell science 2014 Sep 15;127(Pt 18):3928-42
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.
Uchil PD, Hinz A, Siegel S, Coenen-Stass A, Pertel T, Luban J, Mothes W
Journal of virology 2013 Jan;87(1):257-72
Journal of virology 2013 Jan;87(1):257-72
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 13623-1-AP(TRIM15 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using TRIM15 antibody 13623-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line