MAB6561-100

antibody from R&D Systems

Targeting: ALCAM CD166, MEMD

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB6561-100

Provider

R&D Systems

Product name

Human ALCAM/CD166 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from ascites. Detects human ALCAM/CD166 in Western blots. Shows approximately 50% cross-reactivity with recombinant mouse OCAM and no cross-reactivity with recombinant human (rh) BCAM, rhEpCAM, rhMCAM, or rhNCAM-L1.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

Q13740


Isotype

IgG

Antibody clone number

105902

Vial size

100 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Fluoxetine induces direct inhibitory effects on mesenchymal stem cell‑derived osteoprogenitor cells independent of serotonin concentration.

Koura SM, Salama M, El-Hussiny M, Khalil MEA, Lotfy A, Hassan SA, Gad Elhak SA, Sobh MA
Molecular medicine reports 2019 Apr;19(4):2611-2619

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Alternative splicing of ALCAM enables tunable regulation of cell-cell adhesion through differential proteolysis.

Hebron KE, Li EY, Arnold Egloff SA, von Lersner AK, Taylor C, Houkes J, Flaherty DK, Eskaros A, Stricker TP, Zijlstra A
Scientific reports 2018 Feb 16;8(1):3208

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Elevated ALCAM shedding in colorectal cancer correlates with poor patient outcome.

Hansen AG, Freeman TJ, Arnold SA, Starchenko A, Jones-Paris CR, Gilger MA, Washington MK, Fan KH, Shyr Y, Beauchamp RD, Zijlstra A
Cancer research 2013 May 15;73(10):2955-64

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Relevance of activated leukocyte cell adhesion molecule (ALCAM) in tumor tissue and sera of cervical cancer patients.

Ihnen M, Kress K, Kersten JF, Kilic E, Choschzick M, Zander H, Müller V, Mahner S, Jänicke F, Woelber L, Milde-Langosch K
BMC cancer 2012 Apr 4;12:140

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Activated leukocyte cell adhesion molecule: a novel biomarker for breast cancer.

Kulasingam V, Zheng Y, Soosaipillai A, Leon AE, Gion M, Diamandis EP
International journal of cancer 2009 Jul 1;125(1):9-14

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Phenotypic characterization of human colorectal cancer stem cells.

Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF
Proceedings of the National Academy of Sciences of the United States of America 2007 Jun 12;104(24):10158-63