RA0010

antibody from Oursmab

Targeting: ALCAM CD166, MEMD

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0010

Provider

Oursmab

Product name

Praluzatamab (Biosimilar Reference Antibody) (ALCAM)

Antibody type

Monoclonal

Description

Praluzatamab is a monoclonal antibody (IgG1 kappa) developed for targeted therapy, primarily in oncology. Its primary mechanism of action is the specific binding to Activated Leukocyte Cell Adhesion Molecule (ALCAM), also known as CD166. While the exact therapeutic modality (e.g., as a naked antibody to block pro-tumorigenic signaling, or as an antibody-drug conjugate/ADC to deliver a cytotoxic payload) would determine its final mechanism, its core function is to specifically recognize and engage ALCAM-expressing cells, potentially inhibiting tumor growth, metastasis, or inducing direct cell death.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Praluzatamab (Biosimilar Reference Antibody) (ALCAM)-RA0010-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Praluzatamab (Biosimilar Reference Antibody) (ALCAM)-RA0010 in a linear range of 15.63¨C125 ng/mL.