ABIN562043

antibody from antibodies-online

Targeting: SLC11A2 DCT1, DMT1, NRAMP2

Western blot (Recommended by provider)

ELISA (Supportive data in Antibodypedia)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN562043

Provider

antibodies-online

Product name

anti-Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) (AA 1-65), (partial) antibody

Antibody type

Monoclonal

Reactivity

Human

Host

Mouse

Epitope

AA 1-65, partial

Isotype

IgG

Antibody clone number

4C6

Vial size

100 μg

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Handling

Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2.

Montalbetti N, Simonin A, Simonin C, Awale M, Reymond JL, Hediger MA
Biochemical pharmacology 2015 Aug 1;96(3):216-24

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Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra.

Montalbetti N, Simonin A, Dalghi MG, Kovacs G, Hediger MA
Journal of biomolecular screening 2014 Jul;19(6):900-8

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Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.

Howitt J, Putz U, Lackovic J, Doan A, Dorstyn L, Cheng H, Yang B, Chan-Ling T, Silke J, Kumar S, Tan SS
Proceedings of the National Academy of Sciences of the United States of America 2009 Sep 8;106(36):15489-94

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Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.

Foot NJ, Dalton HE, Shearwin-Whyatt LM, Dorstyn L, Tan SS, Yang B, Kumar S
Blood 2008 Nov 15;112(10):4268-75

ELISA

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

ELISA