Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 23395-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- PIAS1 antibody
- Antibody type
- Polyclonal
- Description
- PIAS1 antibody (Cat. #23395-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NSMCE2 dispensability in mouse spermatogenesis suggests functional redundancy within the meiotic repair network.
Targeting the interaction between long noncoding RNA XR_001779380 and Prdm1 to enhance IFN-Îł immunity in murine neonatal intestinal epithelial cells.
Inhibition of HMGN2 SUMOylation ameliorates atherosclerosis by activating PAX5 expression to induce macrophage M2 polarization.
Dysregulation of protein SUMOylation networks in Huntington's disease R6/2 mouse striatum.
Effect and underlying mechanism of Huangjing Qianshi decoction in pre-diabetes mouse model.
SUMO E3 ligase MUL1 inhibits lymph node metastasis of bladder cancer by mediating mitochondrial HSPA9 translocation.
Diammonium glycyrrhizinate ameliorates alcohol-induced liver injury by reducing oxidative stress, steatosis, and inflammation.
PIAS1 upregulation confers protection against Cerulein-induced acute pancreatitis via FTO downregulation by enhancing sumoylation of Foxa2.
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons.
SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer.
PIAS1 Alleviates Hepatic Ischemia-Reperfusion Injury in Mice through a Mechanism Involving NFATc1 SUMOylation.
Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin.
PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence.
miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.
Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.
Qin Z, Xiong Q, Wang M, Fang Y, Fan Q, Ma B, Gao Y, Cheng M, Cao Y, Zhang Y
Frontiers in cell and developmental biology 2026;14:1751806
Frontiers in cell and developmental biology 2026;14:1751806
Targeting the interaction between long noncoding RNA XR_001779380 and Prdm1 to enhance IFN-Îł immunity in murine neonatal intestinal epithelial cells.
Jin K, Gong A-Y, Wang S, Martins GA, Strauss-Soukup JK, O'Connor RM, Chen X-M
mBio 2025 Jul 9;16(7):e0077325
mBio 2025 Jul 9;16(7):e0077325
Inhibition of HMGN2 SUMOylation ameliorates atherosclerosis by activating PAX5 expression to induce macrophage M2 polarization.
Wang X, Wu P, Shen Y, Xu S, Wan Q, Yang Y
Experimental cell research 2025 Aug 15;451(2):114709
Experimental cell research 2025 Aug 15;451(2):114709
Dysregulation of protein SUMOylation networks in Huntington's disease R6/2 mouse striatum.
Kachemov M, Vaibhav V, Smith C, Sundararaman N, Heath M, Pendlebury DF, Matlock A, Lau A, Morozko E, Lim RG, Reidling J, Steffan JS, Van Eyk JE, Thompson LM
Brain : a journal of neurology 2025 Apr 3;148(4):1212-1227
Brain : a journal of neurology 2025 Apr 3;148(4):1212-1227
Effect and underlying mechanism of Huangjing Qianshi decoction in pre-diabetes mouse model.
Cai J, Zhu Y, Deng G, Ouyang L, Xiao W, Zhou F, Han Y, Yuan F, Huang L, Li X
BMC complementary medicine and therapies 2025 Apr 23;25(1):151
BMC complementary medicine and therapies 2025 Apr 23;25(1):151
SUMO E3 ligase MUL1 inhibits lymph node metastasis of bladder cancer by mediating mitochondrial HSPA9 translocation.
Wu J, Huang M, Dong W, Chen Y, Zhou Q, Zhang Q, Zheng J, Liu Y, Zhang Y, Liu S, Yang C, Chen S, Huang J, Lin T, Chen X
International journal of biological sciences 2024;20(10):3986-4006
International journal of biological sciences 2024;20(10):3986-4006
Diammonium glycyrrhizinate ameliorates alcohol-induced liver injury by reducing oxidative stress, steatosis, and inflammation.
Wang X, Gao X, Xu F, Niu J, Wang Z
International immunopharmacology 2024 Dec 25;143(Pt 2):113374
International immunopharmacology 2024 Dec 25;143(Pt 2):113374
PIAS1 upregulation confers protection against Cerulein-induced acute pancreatitis via FTO downregulation by enhancing sumoylation of Foxa2.
Zhou J, Tan Q, Tong J, Tong Z, Wang C, Sun B, Fang M, Lv J
Genomics 2023 Sep;115(5):110693
Genomics 2023 Sep;115(5):110693
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
Gu C, Gao F, Zhang S, Kang L, Zhang W, Feng X, Liu J, Tian Y, Wei Q, Du Y, Xing Y, Liu Q, Liu S
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons.
Wu GH, Smith-Geater C, Galaz-Montoya JG, Gu Y, Gupte SR, Aviner R, Mitchell PG, Hsu J, Miramontes R, Wang KQ, Geller NR, Hou C, Danita C, Joubert LM, Schmid MF, Yeung S, Frydman J, Mobley W, Wu C, Thompson LM, Chiu W
Nature communications 2023 Feb 8;14(1):692
Nature communications 2023 Feb 8;14(1):692
SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer.
Wu C, Zhu X, Dai Q, Chu Z, Yang S, Dong Z
Frontiers in bioscience (Landmark edition) 2023 Aug 31;28(8):192
Frontiers in bioscience (Landmark edition) 2023 Aug 31;28(8):192
PIAS1 Alleviates Hepatic Ischemia-Reperfusion Injury in Mice through a Mechanism Involving NFATc1 SUMOylation.
Luo J, Li J, Li T, Zhang Z, Chen G, Li Q, Qi H, Si Z
Disease markers 2022;2022:4988539
Disease markers 2022;2022:4988539
Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin.
Zhang T, Yang H, Zhou Z, Bai Y, Wang J, Wang W
Nature communications 2022 Sep 1;13(1):5133
Nature communications 2022 Sep 1;13(1):5133
PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence.
Wang G, Zhao Y, Zhou Y, Jiang L, Liang L, Kong F, Yan Y, Wang X, Wang Y, Wen X, Zeng X, Tian G, Deng G, Shi J, Liu L, Chen H, Li C
PLoS pathogens 2022 Apr;18(4):e1010446
PLoS pathogens 2022 Apr;18(4):e1010446
miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.
Xiao Y, Huang W, Huang H, Wang L, Wang M, Zhang T, Fang X, Xia X
DNA and cell biology 2021 Apr;40(4):618-628
DNA and cell biology 2021 Apr;40(4):618-628
Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.
Wu J, Lai X, Cui G, Chen Q, Liu J, Kang Y, Zhang Y, Feng X, Hu C, Shao L
Journal of hazardous materials 2020 Nov 15;399:122809
Journal of hazardous materials 2020 Nov 15;399:122809
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PIAS1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PIAS1. This antibody recognizes human antigen. The PIAS1 antibody has been validated for the following applications: ELISA, WB analysis.