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- Product number
- ABIN2845660 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 100-130), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 100-130, N-Term
- Antibody clone number
- RB0668
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Identification of novel interacting partners of Sirtuin6.
Substantially reduced expression of PIAS1 is associated with colon cancer development.
PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription.
Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators.
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1).
Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes.
Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activation.
Polyakova O, Borman S, Grimley R, Vamathevan J, Hayes B, Solari R
PloS one 2012;7(12):e51555
PloS one 2012;7(12):e51555
Substantially reduced expression of PIAS1 is associated with colon cancer development.
Coppola D, Parikh V, Boulware D, Blanck G
Journal of cancer research and clinical oncology 2009 Sep;135(9):1287-91
Journal of cancer research and clinical oncology 2009 Sep;135(9):1287-91
PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription.
Nishida T, Yasuda H
The Journal of biological chemistry 2002 Nov 1;277(44):41311-7
The Journal of biological chemistry 2002 Nov 1;277(44):41311-7
Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators.
Tan JA, Hall SH, Hamil KG, Grossman G, Petrusz P, French FS
The Journal of biological chemistry 2002 May 10;277(19):16993-7001
The Journal of biological chemistry 2002 May 10;277(19):16993-7001
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1).
Megidish T, Xu JH, Xu CW
The Journal of biological chemistry 2002 Mar 8;277(10):8255-9
The Journal of biological chemistry 2002 Mar 8;277(10):8255-9
Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes.
Miyauchi Y, Yogosawa S, Honda R, Nishida T, Yasuda H
The Journal of biological chemistry 2002 Dec 20;277(51):50131-6
The Journal of biological chemistry 2002 Dec 20;277(51):50131-6
Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activation.
Liu B, Shuai K
The Journal of biological chemistry 2001 Sep 28;276(39):36624-31
The Journal of biological chemistry 2001 Sep 28;276(39):36624-31
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Supportive validation
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