Antibody data

Product number
Ab099911 - Provider product page
Provider
Aladdin Scientific
Product name
Dishevelled/Dvl1 Antibody
Antibody type
Polyclonal
Description
Rabbit anti Human Dishevelled/Dvl1 Antibody, Polyclonal, could be used for WB, IHC and so on.Application:WB: 0.01-2µg/mLIHC: 5-20µg/mLProtein FunctionParticipates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 150-285
Vial size
100_l,10_l,1ml,20_l,50_l
Concentration
Lot by Lot
Storage
Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
DVL1 protein structure - Ab099911 shown in red.