Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11548-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11548-1-AP, RRID:AB_2290243
- Product name
- Antizyme inhibitor 1 antibody
- Antibody type
- Polyclonal
- Description
- Antizyme inhibitor 1 antibody (Cat. #11548-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inflammation primes the kidney for recovery by activating AZIN1 A-to-I editing.
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing.
AZIN1 RNA editing alters protein interactions, leading to nuclear translocation and worse outcomes in prostate cancer.
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.
The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.
Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433.
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Pancreatic Kininogenase Ameliorates Renal Fibrosis in Streptozotocin Induced-Diabetic Nephropathy Rat.
The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.
The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway.
Heruye S, Myslinski J, Zeng C, Zollman A, Makino S, Nanamatsu A, Mir Q, Janga SC, Doud EH, Eadon MT, Maier B, Hamada M, Tran TM, Dagher PC, Hato T
bioRxiv : the preprint server for biology 2023 Nov 9;
bioRxiv : the preprint server for biology 2023 Nov 9;
ADAR1 affects gastric cancer cell metastasis and reverses cisplatin resistance through AZIN1.
Wang H, Yang L, Liu R, He H, Zhang M, Xu Y
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
Anti-cancer drugs 2023 Nov 1;34(10):1132-1145
RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing.
Xing Y, Nakahama T, Wu Y, Inoue M, Kim JI, Todo H, Shibuya T, Kato Y, Kawahara Y
The Journal of biological chemistry 2023 Jul;299(7):104840
The Journal of biological chemistry 2023 Jul;299(7):104840
AZIN1 RNA editing alters protein interactions, leading to nuclear translocation and worse outcomes in prostate cancer.
Ghalali A, Wang L, Stopsack KH, Rice JM, Wu S, Wu CL, Zetter BR, Rogers MS
Experimental & molecular medicine 2022 Oct;54(10):1713-1726
Experimental & molecular medicine 2022 Oct;54(10):1713-1726
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.
Tay DJT, Song Y, Peng B, Toh TB, Hooi L, Toh DK, Hong H, Tang SJ, Han J, Gan WL, Chan THM, Krishna MS, Patil KM, Maraswami M, Loh TP, Dan YY, Zhou L, Bonney GK, Chow PK, Chen G, Chow EK, Le MTN, Chen L
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Nov 3;29(11):3258-3273
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Nov 3;29(11):3258-3273
The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.
Chai X, Zhan J, Pan J, He M, Li B, Wang J, Ma H, Wang Y, Liu S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):10907-12921
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):10907-12921
Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433.
Zhu Y, Pan W, Yang T, Meng X, Jiang Z, Tao L, Wang L
Frontiers in genetics 2019;10:564
Frontiers in genetics 2019;10:564
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA
The Journal of clinical investigation 2018 Oct 1;128(10):4682-4696
The Journal of clinical investigation 2018 Oct 1;128(10):4682-4696
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Tao L, Bei Y, Chen P, Lei Z, Fu S, Zhang H, Xu J, Che L, Chen X, Sluijter JP, Das S, Cretoiu D, Xu B, Zhong J, Xiao J, Li X
Theranostics 2016;6(12):2068-2083
Theranostics 2016;6(12):2068-2083
Pancreatic Kininogenase Ameliorates Renal Fibrosis in Streptozotocin Induced-Diabetic Nephropathy Rat.
Zhu D, Zhang L, Cheng L, Ren L, Tang J, Sun D
Kidney & blood pressure research 2016;41(1):9-17
Kidney & blood pressure research 2016;41(1):9-17
The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.
Han L, Diao L, Yu S, Xu X, Li J, Zhang R, Yang Y, Werner HMJ, Eterovic AK, Yuan Y, Li J, Nair N, Minelli R, Tsang YH, Cheung LWT, Jeong KJ, Roszik J, Ju Z, Woodman SE, Lu Y, Scott KL, Li JB, Mills GB, Liang H
Cancer cell 2015 Oct 12;28(4):515-528
Cancer cell 2015 Oct 12;28(4):515-528
The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway.
Li R, Chung AC, Dong Y, Yang W, Zhong X, Lan HY
Kidney international 2013 Dec;84(6):1129-44
Kidney international 2013 Dec;84(6):1129-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 11548-1-AP(AZIN1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using AZIN1 antibody 11548-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 11548-1-AP(AZIN1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue