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- References [25]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 18258-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18258-1-AP, RRID:AB_2130658
- Product name
- ATG13 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATG13 antibody (Cat. #18258-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Monosodium Glutamate Exposure and Liver Damage: Modulatory Effects of L-Carnitine on Inflammation and Autophagy.
S-palmitoylation coordinates the trafficking of ATG9A to mediate autophagy initiation.
BNST(GABA) neurons regulate autophagy to alleviate depression with gastric dysfunction symptoms.
Genetic depletion of early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
ETAS(®), a Standardized Extract of Asparagus officinalis Stem, Alleviates Sarcopenia via Regulating Protein Turnover and Mitochondrial Quality.
Silencing of tropomodulin 1 inhibits acute myeloid leukemia cell proliferation and tumor growth by elevating karyopherin alpha 2-mediated autophagy.
Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease.
Inhibition of Amino Acids Influx into Proximal Tubular Cells Improves Lysosome Function in Diabetes.
Effect of beta-cypermethrin on the reproductive capacity of female mice in advanced age.
An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.
TFAM knockdown undermines SQSTM1 mRNA stability but retards autophagy flux and inhibits tumor cells proliferation under starvation conditions.
Silencing TUFM Inhibits Development of Monocrotaline-Induced Pulmonary Hypertension by Regulating Mitochondrial Autophagy via AMPK/mTOR Signal Pathway.
Brucea javanica Oil Emulsion Promotes Autophagy in Ovarian Cancer Cells Through the miR-8485/LAMTOR3/mTOR/ATG13 Signaling Axis.
MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy.
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE).
Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling.
Downregulation of beclin 1 restores arsenite-induced impaired autophagic flux by improving the lysosomal function in the brain.
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease.
Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy.
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Noncanonical autophagy promotes the visual cycle.
Toriola MA, Timlin E, Bulbule S, Reyes A, Adedeji OM, Gottschalk CG, Barua A, Arnold LA, Roy A
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Jan 27;75(1):26
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Jan 27;75(1):26
Monosodium Glutamate Exposure and Liver Damage: Modulatory Effects of L-Carnitine on Inflammation and Autophagy.
Kalkan KT, Pektas F
Journal of applied toxicology : JAT 2026 Apr;46(4):1361-1371
Journal of applied toxicology : JAT 2026 Apr;46(4):1361-1371
S-palmitoylation coordinates the trafficking of ATG9A to mediate autophagy initiation.
Xia F, Li W, Wang W, Liu J, Li X, Cai J, Shan H, Cai Z, Cui J
Autophagy 2025 Nov;21(11):2422-2442
Autophagy 2025 Nov;21(11):2422-2442
BNST(GABA) neurons regulate autophagy to alleviate depression with gastric dysfunction symptoms.
Yuan Y, Xu J, Zhu S, Ma H, Wang H, Wang X, Shen G
Brain research bulletin 2025 Jun 15;226:111360
Brain research bulletin 2025 Jun 15;226:111360
Genetic depletion of early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Toriola MA, Timlin E, Bulbule S, Reyes A, Adedeji OM, Gottschalk CG, Barua A, Arnold LA, Roy A
Research square 2025 Aug 6;
Research square 2025 Aug 6;
ETAS(®), a Standardized Extract of Asparagus officinalis Stem, Alleviates Sarcopenia via Regulating Protein Turnover and Mitochondrial Quality.
Chang SJ, Chen YC, Chang YC, Cheng CC, Chan YC
Pharmaceuticals (Basel, Switzerland) 2025 Aug 22;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Aug 22;18(9)
Silencing of tropomodulin 1 inhibits acute myeloid leukemia cell proliferation and tumor growth by elevating karyopherin alpha 2-mediated autophagy.
Xia Y, Wang D, Zhao H, Meng T, Jiang Q, Pan Z, Wang G, An T, Li B, Bi S, Wang H, Lu J, Liu H, Lin H, Lin C, Zheng Q, Li D
Pharmacological research 2024 Sep;207:107327
Pharmacological research 2024 Sep;207:107327
Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease.
Bagh MB, Appu AP, Sadhukhan T, Mondal A, Plavelil N, Raghavankutty M, Supran AM, Sadhukhan S, Liu A, Mukherjee AB
The Journal of biological chemistry 2024 Feb;300(2):105641
The Journal of biological chemistry 2024 Feb;300(2):105641
Inhibition of Amino Acids Influx into Proximal Tubular Cells Improves Lysosome Function in Diabetes.
Kano Y, Yamaguchi S, Mise K, Kawakita C, Onishi Y, Kurooka N, Sugawara R, Albuayjan HHH, Nakatsuka A, Eguchi J, Wada J
Kidney360 2024 Feb 1;5(2):182-194
Kidney360 2024 Feb 1;5(2):182-194
Effect of beta-cypermethrin on the reproductive capacity of female mice in advanced age.
Qiao QF, Wang LQ, Yu DE, Li N, Xu QJ, Zhou YJ
Environmental toxicology and pharmacology 2024 Apr;107:104410
Environmental toxicology and pharmacology 2024 Apr;107:104410
An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.
Liang P, Zhang J, Wu Y, Zheng S, Xu Z, Yang S, Wang J, Ma S, Xiao L, Hu T, Jiang W, Huang C, Xing Q, Kundu M, Wang B
EMBO reports 2023 Nov 6;24(11):e56850
EMBO reports 2023 Nov 6;24(11):e56850
TFAM knockdown undermines SQSTM1 mRNA stability but retards autophagy flux and inhibits tumor cells proliferation under starvation conditions.
Jiang X, Xu Y, Yang J, Wang J, Gao L, Yu L
Cell biology international 2023 Aug;47(8):1453-1465
Cell biology international 2023 Aug;47(8):1453-1465
Silencing TUFM Inhibits Development of Monocrotaline-Induced Pulmonary Hypertension by Regulating Mitochondrial Autophagy via AMPK/mTOR Signal Pathway.
Wei R, Lv X, Fang C, Liu C, Ma Z, Liu K
Oxidative medicine and cellular longevity 2022;2022:4931611
Oxidative medicine and cellular longevity 2022;2022:4931611
Brucea javanica Oil Emulsion Promotes Autophagy in Ovarian Cancer Cells Through the miR-8485/LAMTOR3/mTOR/ATG13 Signaling Axis.
Wang Y, Chen B, Xiao M, Wang X, Peng Y
Frontiers in pharmacology 2022;13:935155
Frontiers in pharmacology 2022;13:935155
MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy.
Lv Z, Qiu X, Jin P, Li Z, Zhang Y, Lv L, Song F
Life (Basel, Switzerland) 2022 Oct 20;12(10)
Life (Basel, Switzerland) 2022 Oct 20;12(10)
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Zhou Y, Li ZX, Liu YT, Xu ZC, Hu Y, Lv W, Yang ZY, Sheng YM, Liu S
Brain research bulletin 2022 Oct 1;188:203-213
Brain research bulletin 2022 Oct 1;188:203-213
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE).
Gottschalk G, Peterson D, Knox K, Maynard M, Whelan RJ, Roy A
Molecular and cellular neurosciences 2022 May;120:103731
Molecular and cellular neurosciences 2022 May;120:103731
Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling.
Li MZ, Liu EJ, Zhou QZ, Li SH, Liu SJ, Yu HT, Pan QH, Sun F, He T, Wang WJ, Ke D, Feng YQ, Li J, Wang JZ
Military Medical Research 2022 Jul 7;9(1):38
Military Medical Research 2022 Jul 7;9(1):38
Downregulation of beclin 1 restores arsenite-induced impaired autophagic flux by improving the lysosomal function in the brain.
Zhou H, Ling H, Li Y, Jiang X, Cheng S, Zubeir GM, Xia Y, Qin X, Zhang J, Zou Z, Chen C
Ecotoxicology and environmental safety 2022 Jan 1;229:113066
Ecotoxicology and environmental safety 2022 Jan 1;229:113066
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease.
Ma Z, Li L, Livingston MJ, Zhang D, Mi Q, Zhang M, Ding HF, Huo Y, Mei C, Dong Z
The Journal of clinical investigation 2020 Sep 1;130(9):5011-5026
The Journal of clinical investigation 2020 Sep 1;130(9):5011-5026
Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy.
You M, Miao Z, Tian J, Hu F
European journal of nutrition 2020 Oct;59(7):2875-2892
European journal of nutrition 2020 Oct;59(7):2875-2892
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
You M, Miao Z, Sienkiewicz O, Jiang X, Zhao X, Hu F
International immunopharmacology 2020 Jul;84:106501
International immunopharmacology 2020 Jul;84:106501
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Ho WY, Tai YK, Chang JC, Liang J, Tyan SH, Chen S, Guan JL, Zhou H, Shen HM, Koo E, Ling SC
Autophagy 2019 May;15(5):827-842
Autophagy 2019 May;15(5):827-842
Noncanonical autophagy promotes the visual cycle.
Kim JY, Zhao H, Martinez J, Doggett TA, Kolesnikov AV, Tang PH, Ablonczy Z, Chan CC, Zhou Z, Green DR, Ferguson TA
Cell 2013 Jul 18;154(2):365-76
Cell 2013 Jul 18;154(2):365-76
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 18258-1-AP(KIAA0652 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 18258-1-AP(KIAA0652 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATG13 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATG13. This antibody recognizes human,mouse,rat antigen. The ATG13 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
