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- References [23]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16534-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16534-1-AP, RRID:AB_2087511
- Product name
- CTHRC1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CTHRC1 antibody (Cat. #16534-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references E3 ubiquitin ligase NEDD4L inhibits epithelial-mesenchymal transition by suppressing the β-catenin/HIF-1α positive feedback loop in chronic rhinosinusitis with nasal polyps.
Collagen Triple Helix Repeat Containing 1 Deficiency Protects Against Airway Remodeling and Inflammation in Asthma Models In Vivo and In Vitro.
CTHRC1 is associated with immune cell infiltration and functions as an adverse marker for prognosis in head and neck squamous cell carcinoma.
The molecular mechanisms of CTHRC1 in gastric cancer by integrating TCGA, GEO and GSA datasets.
Single-cell landscape reveals active cell subtypes and their interaction in the tumor microenvironment of gastric cancer.
Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation.
Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA Sequencing.
MicroRNA Hsa-Let-7b Regulates the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Targeting CTHRC1.
NEDD4L-induced β-catenin ubiquitination suppresses the formation and progression of interstitial pulmonary fibrosis via inhibiting the CTHRC1/HIF-1α axis.
Hyperdense Pancreatic Ductal Adenocarcinoma: Clinical Characteristics and Proteomic Landscape.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
CTHRC1 affects malignant tumor cell behavior and is regulated by miR-30e-5p in human prostate cancer.
CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular Carcinoma.
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1.
CTHRC1 promotes M2-like macrophage recruitment and myometrial invasion in endometrial carcinoma by integrin-Akt signaling pathway.
CTHRC1 mediates IL‑1β‑induced apoptosis in chondrocytes via JNK1/2 signaling.
Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer.
Lentivirus-Mediated Knockdown of CTHRC1 Inhibits Osteosarcoma Cell Proliferation and Migration.
SP1-mediated microRNA-520d-5p suppresses tumor growth and metastasis in colorectal cancer by targeting CTHRC1.
MiR-9 inhibits Schwann cell migration by targeting Cthrc1 following sciatic nerve injury.
Chen SY, Liu PQ, Qin DX, Lv H, Zhou HQ, Xu Y
Acta pharmacologica Sinica 2024 Apr;45(4):831-843
Acta pharmacologica Sinica 2024 Apr;45(4):831-843
Collagen Triple Helix Repeat Containing 1 Deficiency Protects Against Airway Remodeling and Inflammation in Asthma Models In Vivo and In Vitro.
Feng Y, Hu J, Liu F, Shang Y
Inflammation 2023 Jun;46(3):925-940
Inflammation 2023 Jun;46(3):925-940
CTHRC1 is associated with immune cell infiltration and functions as an adverse marker for prognosis in head and neck squamous cell carcinoma.
Zhong R, Yang M, Zhu R, Zhang J, Wang L
Oncology letters 2023 Apr;25(4):133
Oncology letters 2023 Apr;25(4):133
The molecular mechanisms of CTHRC1 in gastric cancer by integrating TCGA, GEO and GSA datasets.
Zhao L, Wang W, Niu P, Luan X, Zhao D, Chen Y
Frontiers in genetics 2022;13:900124
Frontiers in genetics 2022;13:900124
Single-cell landscape reveals active cell subtypes and their interaction in the tumor microenvironment of gastric cancer.
Li Y, Hu X, Lin R, Zhou G, Zhao L, Zhao D, Zhang Y, Li W, Zhang Y, Ma P, Ren H, Liao X, Niu P, Wang T, Zhang X, Wang W, Gao R, Li Q, Church G, He J, Chen Y
Theranostics 2022;12(8):3818-3833
Theranostics 2022;12(8):3818-3833
Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation.
Jyothula SSK, Peters A, Liang Y, Bi W, Shivshankar P, Yau S, Garcha PS, Yuan X, Akkanti B, Collum S, Wareing N, Thandavarayan RA, Poli de Frias F, Rosas IO, Zhao B, Buja LM, Eltzschig HK, Huang HJ, Karmouty-Quintana H
EBioMedicine 2022 Dec;86:104351
EBioMedicine 2022 Dec;86:104351
Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA Sequencing.
Li H, Peng H, Hong W, Wei Y, Tian H, Huang X, Jia L, Zheng J, Duan T, He Q, Wang K
Cells 2022 Dec 25;12(1)
Cells 2022 Dec 25;12(1)
MicroRNA Hsa-Let-7b Regulates the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Targeting CTHRC1.
Fu L, Li N, Ye Y, Ye X, Xiao T, Wu X, Ma Y, Yu J
Stem cells international 2021;2021:5791181
Stem cells international 2021;2021:5791181
NEDD4L-induced β-catenin ubiquitination suppresses the formation and progression of interstitial pulmonary fibrosis via inhibiting the CTHRC1/HIF-1α axis.
Chen L, Yang Y, Yan H, Peng X, Zou J
International journal of biological sciences 2021;17(13):3320-3330
International journal of biological sciences 2021;17(13):3320-3330
Hyperdense Pancreatic Ductal Adenocarcinoma: Clinical Characteristics and Proteomic Landscape.
Xu H, Hua J, Meng Q, Wang X, Xu J, Wang W, Zhang B, Liu J, Liang C, Yu X, Shi S
Frontiers in oncology 2021;11:640820
Frontiers in oncology 2021;11:640820
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Morani F, Bisceglia L, Rosini G, Mutti L, Melaiu O, Landi S, Gemignani F
International journal of molecular sciences 2021 Mar 8;22(5)
International journal of molecular sciences 2021 Mar 8;22(5)
CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway.
Bai Y, Yin K, Su T, Ji F, Zhang S
OncoTargets and therapy 2020;13:5743-5753
OncoTargets and therapy 2020;13:5743-5753
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
CTHRC1 affects malignant tumor cell behavior and is regulated by miR-30e-5p in human prostate cancer.
Ma Z, Chao F, Wang S, Song Z, Zhuo Z, Zhang J, Xu G, Chen G
Biochemical and biophysical research communications 2020 Apr 30;525(2):418-424
Biochemical and biophysical research communications 2020 Apr 30;525(2):418-424
CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular Carcinoma.
Zhou H, Su L, Liu C, Li B, Li H, Xie Y, Sun D
OncoTargets and therapy 2019;12:7823-7831
OncoTargets and therapy 2019;12:7823-7831
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1.
Jin J, Togo S, Kadoya K, Tulafu M, Namba Y, Iwai M, Watanabe J, Nagahama K, Okabe T, Hidayat M, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Sasaki S, Tominaga S, Takahashi K
Respiratory research 2019 Jun 11;20(1):119
Respiratory research 2019 Jun 11;20(1):119
CTHRC1 promotes M2-like macrophage recruitment and myometrial invasion in endometrial carcinoma by integrin-Akt signaling pathway.
Li LY, Yin KM, Bai YH, Zhang ZG, Di W, Zhang S
Clinical & experimental metastasis 2019 Aug;36(4):351-363
Clinical & experimental metastasis 2019 Aug;36(4):351-363
CTHRC1 mediates IL‑1β‑induced apoptosis in chondrocytes via JNK1/2 signaling.
Zhang Q, Yin ZS, Zhang FW, Cao K, Sun HY
International journal of molecular medicine 2018 Apr;41(4):2270-2278
International journal of molecular medicine 2018 Apr;41(4):2270-2278
Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer.
Guo B, Yan H, Li L, Yin K, Ji F, Zhang S
Journal of ovarian research 2017 Oct 11;10(1):69
Journal of ovarian research 2017 Oct 11;10(1):69
Lentivirus-Mediated Knockdown of CTHRC1 Inhibits Osteosarcoma Cell Proliferation and Migration.
Sang W, Zhu L, Ma J, Lu H, Wang C
Cancer biotherapy & radiopharmaceuticals 2016 Apr;31(3):91-8
Cancer biotherapy & radiopharmaceuticals 2016 Apr;31(3):91-8
SP1-mediated microRNA-520d-5p suppresses tumor growth and metastasis in colorectal cancer by targeting CTHRC1.
Yan L, Yu J, Tan F, Ye GT, Shen ZY, Liu H, Zhang Y, Wang JF, Zhu XJ, Li GX
American journal of cancer research 2015;5(4):1447-59
American journal of cancer research 2015;5(4):1447-59
MiR-9 inhibits Schwann cell migration by targeting Cthrc1 following sciatic nerve injury.
Zhou S, Gao R, Hu W, Qian T, Wang N, Ding G, Ding F, Yu B, Gu X
Journal of cell science 2014 Mar 1;127(Pt 5):967-76
Journal of cell science 2014 Mar 1;127(Pt 5):967-76
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 16534-1-AP(CTHRC1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 16534-1-AP(CTHRC1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CTHRC1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CTHRC1. This antibody recognizes human,mouse,rat antigen. The CTHRC1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
