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- Antibody Data
- Antigen structure
- References [21]
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- Product number
- 16610-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ATAD3A/B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATAD3A/B antibody (Cat. #16610-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway.
The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagy.
A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness.
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière's disease.
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling.
NEK10 kinase ablation affects mitochondrial morphology, function and protein phosphorylation status.
Ubiquitination of ATAD3A by TRIM25 exacerbates cerebral ischemia-reperfusion injury via regulating PINK1/Parkin signaling pathway-mediated mitophagy.
High-throughput tagging of endogenous loci for rapid characterization of protein function.
NDUFS4 regulates cristae remodeling in diabetic kidney disease.
Absence of both MGME1 and POLG EXO abolishes mtDNA whereas absence of either creates unique mtDNA duplications.
Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis.
Analysis of Radiation Toxicity in Mammalian Cells Stably Transduced with Mitochondrial Stat3.
Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury.
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly.
ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA.
OPA1 and MICOS Regulate mitochondrial crista dynamics and formation.
Novel ATAD3A recessive mutation associated to fatal cerebellar hypoplasia with multiorgan involvement and mitochondrial structural abnormalities.
ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels.
Guo QQ, Wang SS, Jiang XY, Xie XC, Zou Y, Liu JW, Guo Y, Li YH, Liu XY, Hao S, Zhang XY, Wu XX, Lu SM, Xu HD, Guo WD, Feng YL, Wang CG, Zhang SP, Li JB, Liu C, Song XY, Finkel T, Cao L
Proceedings of the National Academy of Sciences of the United States of America 2025 Oct 7;122(40):e2502841122
Proceedings of the National Academy of Sciences of the United States of America 2025 Oct 7;122(40):e2502841122
The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagy.
Chu WH, Lin YS, Guo J, Jane WN, Wang WJ, Lin YY, Liu PH, Huang PY, Chiang WC
The Journal of biological chemistry 2025 Nov;301(11):110739
The Journal of biological chemistry 2025 Nov;301(11):110739
A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness.
Schlesinger D, Dirks C, Navarro C, Lafranchi L, Spinner A, Raja GL, Mun-Sum Tong G, Eirich J, Martinez TF, Elsässer SJ
iScience 2025 Mar 21;28(3):111884
iScience 2025 Mar 21;28(3):111884
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière's disease.
Harhai M, Foged MM, Zarges C, Landoni JC, Chollet S, Simonelli M, Recazens E, Lisci M, Laban N, Manley S, Riemer J, Lopez-Escamez JA, Lysakowski A, Jourdain AA
Cell reports 2025 Aug 26;44(8):116069
Cell reports 2025 Aug 26;44(8):116069
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
Shi J, Zhao G, Wang S, Wei Y, Wu J, Huang G, Chen J, Xia J
Biotechnology journal 2025 Apr;20(4):e202400611
Biotechnology journal 2025 Apr;20(4):e202400611
MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling.
Rigoni G, Calvo E, Glytsou C, Carro-Alvarellos M, Noguchi M, Semenzato M, Quirin C, Caicci F, Meneghetti N, Sturlese M, Ishihara T, Moro S, Rampazzo C, Ishihara N, Bezzo F, Salviati L, Vazquez J, Sales G, Romualdi C, Enriquez JA, Scorrano L, Soriano ME
Cell metabolism 2025 Apr 1;37(4):1024-1038.e8
Cell metabolism 2025 Apr 1;37(4):1024-1038.e8
NEK10 kinase ablation affects mitochondrial morphology, function and protein phosphorylation status.
de Oliveira AP, Navarro CDC, Dias PRF, Arguello T, Walker BR, Bacman SR, Sousa LM, Castilho RF, Consonni SR, Moraes CT, Kobarg J
Proteome science 2024 Oct 8;22(1):8
Proteome science 2024 Oct 8;22(1):8
Ubiquitination of ATAD3A by TRIM25 exacerbates cerebral ischemia-reperfusion injury via regulating PINK1/Parkin signaling pathway-mediated mitophagy.
Li X, Guan L, Liu Z, Du Z, Yuan Q, Zhou F, Yang X, Lv M, Lv L
Free radical biology & medicine 2024 Nov 1;224:757-769
Free radical biology & medicine 2024 Nov 1;224:757-769
High-throughput tagging of endogenous loci for rapid characterization of protein function.
Kim J, Kratz AF, Chen S, Sheng J, Kim HK, Zhang L, Singh BK, Chavez A
Science advances 2024 May 3;10(18):eadg8771
Science advances 2024 May 3;10(18):eadg8771
NDUFS4 regulates cristae remodeling in diabetic kidney disease.
Mise K, Long J, Galvan DL, Ye Z, Fan G, Sharma R, Serysheva II, Moore TI, Jeter CR, Anna Zal M, Araki M, Wada J, Schumacker PT, Chang BH, Danesh FR
Nature communications 2024 Mar 4;15(1):1965
Nature communications 2024 Mar 4;15(1):1965
Absence of both MGME1 and POLG EXO abolishes mtDNA whereas absence of either creates unique mtDNA duplications.
Gonzalez CD, Nissanka N, Van Booven D, Griswold AJ, Moraes CT
The Journal of biological chemistry 2024 Apr;300(4):107128
The Journal of biological chemistry 2024 Apr;300(4):107128
Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis.
Fu Y, Sacco O, DeBitetto E, Kanshin E, Ueberheide B, Sfeir A
Molecular cell 2023 Oct 19;83(20):3740-3753.e9
Molecular cell 2023 Oct 19;83(20):3740-3753.e9
Analysis of Radiation Toxicity in Mammalian Cells Stably Transduced with Mitochondrial Stat3.
Zanin A, Meneghetti G, Menilli L, Tesoriere A, Argenton F, Mognato M
International journal of molecular sciences 2023 May 4;24(9)
International journal of molecular sciences 2023 May 4;24(9)
Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury.
Chen L, Dong J, Liao S, Wang S, Wu Z, Zuo M, Liu B, Yan C, Chen Y, He H, Meng Q, Song Z
Hepatology (Baltimore, Md.) 2022 Nov;76(5):1389-1408
Hepatology (Baltimore, Md.) 2022 Nov;76(5):1389-1408
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Sen A, Kallabis S, Gaedke F, Jüngst C, Boix J, Nüchel J, Maliphol K, Hofmann J, Schauss AC, Krüger M, Wiesner RJ, Pla-Martín D
Nature communications 2022 Nov 7;13(1):6704
Nature communications 2022 Nov 7;13(1):6704
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
Bao Y, Qiao Y, Yu H, Zhang Z, Yang H, Xin X, Chen Y, Guo Y, Wu N, Jia D
Oxidative medicine and cellular longevity 2021;2021:2514947
Oxidative medicine and cellular longevity 2021;2021:2514947
ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly.
Arguello T, Peralta S, Antonicka H, Gaidosh G, Diaz F, Tu YT, Garcia S, Shiekhattar R, Barrientos A, Moraes CT
Cell reports 2021 Dec 21;37(12):110139
Cell reports 2021 Dec 21;37(12):110139
ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA.
Shu L, Hu C, Xu M, Yu J, He H, Lin J, Sha H, Lu B, Engelender S, Guan M, Song Z
The EMBO journal 2021 Apr 15;40(8):e106283
The EMBO journal 2021 Apr 15;40(8):e106283
OPA1 and MICOS Regulate mitochondrial crista dynamics and formation.
Hu C, Shu L, Huang X, Yu J, Li L, Gong L, Yang M, Wu Z, Gao Z, Zhao Y, Chen L, Song Z
Cell death & disease 2020 Oct 31;11(10):940
Cell death & disease 2020 Oct 31;11(10):940
Novel ATAD3A recessive mutation associated to fatal cerebellar hypoplasia with multiorgan involvement and mitochondrial structural abnormalities.
Peralta S, González-Quintana A, Ybarra M, Delmiro A, Pérez-Pérez R, Docampo J, Arenas J, Blázquez A, Ugalde C, Martín MA
Molecular genetics and metabolism 2019 Dec;128(4):452-462
Molecular genetics and metabolism 2019 Dec;128(4):452-462
ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels.
Peralta S, Goffart S, Williams SL, Diaz F, Garcia S, Nissanka N, Area-Gomez E, Pohjoismäki J, Moraes CT
Journal of cell science 2018 Jul 4;131(13)
Journal of cell science 2018 Jul 4;131(13)
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