Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- AF4990 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Sheep Polyclonal LRRN1/NLRR-1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human LRRN1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human NLRR-3 is observed.
- Reactivity
- Human, Mouse
- Host
- Sheep
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Molecular Logic of Spinocerebellar Tract Neuron Diversity and Connectivity.
Leucine-rich repeat neuronal protein-1 suppresses apoptosis of gastric cancer cells through regulation of Fas/FasL.
Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma.
Baek M, Menon V, Jessell TM, Hantman AW, Dasen JS
Cell reports 2019 May 28;27(9):2620-2635.e4
Cell reports 2019 May 28;27(9):2620-2635.e4
Leucine-rich repeat neuronal protein-1 suppresses apoptosis of gastric cancer cells through regulation of Fas/FasL.
Liu B, Zhang Y, Fan Y, Wang S, Li Z, Deng M, Li C, Wang J, Ma R, Wang X, Wang Y, Xu L, Hou K, Che X, Liu Y, Qu X
Cancer science 2019 Jul;110(7):2145-2155
Cancer science 2019 Jul;110(7):2145-2155
Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma.
Satoh S, Takatori A, Ogura A, Kohashi K, Souzaki R, Kinoshita Y, Taguchi T, Hossain MS, Ohira M, Nakamura Y, Nakagawara A
Scientific reports 2016 Sep 8;6:32682
Scientific reports 2016 Sep 8;6:32682
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- LRRN1/NLRR-1 in Embryonic Mouse Somites. LRRN1/NLRR-1 was detected in immersion fixed frozen sections of embryonic mouse somites (E9.5) using 10 µg/mL Sheep Anti-Human LRRN1/NLRR-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4990) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # NL010) and counterstained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.