BS6910

antibody from Bioworld Technology, Inc
Targeting: SCN4B LQT10
Provider product page for BS6910
Western blot
Immunohistochemistry

Antibody data

Product number
BS6910 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SCN4B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SCN4B.
Description
The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation By similarity. The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10) [MIM:611819]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SCN4B protein structure - BS6910 shown in red.