Antibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [2]
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- Product number
- ABIN396453 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A) (AA 1854-1952) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1854-1952
- Isotype
- IgG
- Antibody clone number
- 4G7
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Biophysical characterisation of the persistent sodium current of the Nav1.6 neuronal sodium channel: a single-channel analysis.
Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population.
Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.
Chatelier A, Zhao J, Bois P, Chahine M
Pflugers Archiv : European journal of physiology 2010 Jun;460(1):77-86
Pflugers Archiv : European journal of physiology 2010 Jun;460(1):77-86
Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects.
Meisler MH, O'Brien JE, Sharkey LM
The Journal of physiology 2010 Jun 1;588(Pt 11):1841-8
The Journal of physiology 2010 Jun 1;588(Pt 11):1841-8
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population.
Wang Y, Zhang J, Liu B, Shao L, Wei Z, Li X, Ji J, Yang F, Wang T, Liu J, Wan C, Li B, Xu Y, Feng G, He L, He G
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2010 Dec;11(8):956-63
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2010 Dec;11(8):956-63
Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.
Elia J, Capasso M, Zaheer Z, Lantieri F, Ambrosini P, Berrettini W, Devoto M, Hakonarson H
Psychiatric genetics 2009 Jun;19(3):134-41
Psychiatric genetics 2009 Jun;19(3):134-41
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB