Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10641-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10641-1-AP, RRID:AB_2240520
- Product name
- TDP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TDP1 antibody (Cat. #10641-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Combined PARP and Dual Topoisomerase Inhibition Potentiates Genome Instability and Cell Death in Ovarian Cancer.
TDP1 is required for efficient non-homologous end joining in human cells.
Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.
Flörkemeier I, Hillmann JS, Weimer JP, Hildebrandt J, Hedemann N, Rogmans C, Dempfle A, Arnold N, Clement B, Bauerschlag DO
International journal of molecular sciences 2022 Sep 10;23(18)
International journal of molecular sciences 2022 Sep 10;23(18)
TDP1 is required for efficient non-homologous end joining in human cells.
Li J, Summerlin M, Nitiss KC, Nitiss JL, Hanakahi LA
DNA repair 2017 Dec;60:40-49
DNA repair 2017 Dec;60:40-49
Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.
Perego P, Cossa G, Tinelli S, Corna E, Carenini N, Gatti L, De Cesare M, Ciusani E, Zunino F, Luison E, Canevari S, Zaffaroni N, Beretta GL
Biochemical pharmacology 2012 Jan 1;83(1):27-36
Biochemical pharmacology 2012 Jan 1;83(1):27-36
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The TDP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TDP1. This antibody recognizes human, mouse, rat antigen. The TDP1 antibody has been validated for the following applications: ELISA, WB analysis.