Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 17781-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17781-1-AP, RRID:AB_2269700
- Product name
- RSPO2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RSPO2 antibody (Cat. #17781-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Desulfovibrio vulgaris interacts with novel gut epithelial immune receptor LRRC19 and exacerbates colitis.
Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/β-catenin pathway.
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritis.
miR-497-5p-RSPO2 axis inhibits cell growth and metastasis in glioblastoma.
R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice.
Role of R-spondin 2 in arterial lymphangiogenesis and atherosclerosis.
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Expression and Prognostic Values of the Roof Plate-Specific Spondin Family in Bladder Cancer.
R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.
RSPO fusion transcripts in colorectal cancer in Japanese population.
Xie R, Gu Y, Li M, Li L, Yang Y, Sun Y, Zhou B, Liu T, Wang S, Liu W, Yang R, Su X, Zhong W, Wang B, Cao H
Microbiome 2024 Jan 3;12(1):4
Microbiome 2024 Jan 3;12(1):4
Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/β-catenin pathway.
Guo D, Pan H, Lu X, Chen Z, Zhou L, Chen S, Huang J, Liang X, Xiao Z, Zeng H, Shao Y, Qi W, Xie D, Lin C
Arthritis research & therapy 2023 Nov 9;25(1):217
Arthritis research & therapy 2023 Nov 9;25(1):217
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritis.
Knights AJ, Farrell EC, Ellis OM, Lammlin L, Junginger LM, Rzeczycki PM, Bergman RF, Pervez R, Cruz M, Knight E, Farmer D, Samani AA, Wu CL, Hankenson KD, Maerz T
Annals of the rheumatic diseases 2023 Feb;82(2):272-282
Annals of the rheumatic diseases 2023 Feb;82(2):272-282
miR-497-5p-RSPO2 axis inhibits cell growth and metastasis in glioblastoma.
Chen K, Wang Z, Zong QB, Zhou MY, Chen QF
Journal of Cancer 2022;13(4):1241-1251
Journal of Cancer 2022;13(4):1241-1251
R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice.
Raslan AA, Oh YJ, Jin YR, Yoon JK
International journal of molecular sciences 2022 Mar 13;23(6)
International journal of molecular sciences 2022 Mar 13;23(6)
Role of R-spondin 2 in arterial lymphangiogenesis and atherosclerosis.
Singla B, Lin HP, Chen A, Ahn W, Ghoshal P, Cherian-Shaw M, White J, Stansfield BK, Csányi G
Cardiovascular research 2021 May 25;117(6):1489-1509
Cardiovascular research 2021 May 25;117(6):1489-1509
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Zhou X, He Y, Li N, Bai G, Pan X, Zhang Z, Zhang H, Li J, Yuan X
Cell death & disease 2021 Jun 26;12(7):653
Cell death & disease 2021 Jun 26;12(7):653
Expression and Prognostic Values of the Roof Plate-Specific Spondin Family in Bladder Cancer.
Gao L, Meng J, Zhang M, Fan S, Gao S, Wang X, Liang C
DNA and cell biology 2020 Jun;39(6):1072-1089
DNA and cell biology 2020 Jun;39(6):1072-1089
R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.
Jackson SR, Costa MFDM, Pastore CF, Zhao G, Weiner AI, Adams S, Palashikar G, Quansah K, Hankenson K, Herbert DR, Vaughan AE
BMC research notes 2020 Feb 4;13(1):54
BMC research notes 2020 Feb 4;13(1):54
RSPO fusion transcripts in colorectal cancer in Japanese population.
Shinmura K, Kahyo T, Kato H, Igarashi H, Matsuura S, Nakamura S, Kurachi K, Nakamura T, Ogawa H, Funai K, Tanahashi M, Niwa H, Sugimura H
Molecular biology reports 2014 Aug;41(8):5375-84
Molecular biology reports 2014 Aug;41(8):5375-84
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The RSPO2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RSPO2. This antibody recognizes human, mouse, rat antigen. The RSPO2 antibody has been validated for the following applications: ELISA, WB analysis.