Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- GTX112027 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX112027, RRID:AB_1950990
- Product name
- NEK8 antibody [N1N2], N-term
- Antibody type
- Polyclonal
- Reactivity
- Human
- Host
- Rabbit
Submitted references Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression.
The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ.
Frank V, Habbig S, Bartram MP, Eisenberger T, Veenstra-Knol HE, Decker C, Boorsma RA, Göbel H, Nürnberg G, Griessmann A, Franke M, Borgal L, Kohli P, Völker LA, Dötsch J, Nürnberg P, Benzing T, Bolz HJ, Johnson C, Gerkes EH, Schermer B, Bergmann C
Human molecular genetics 2013 Jun 1;22(11):2177-85
Human molecular genetics 2013 Jun 1;22(11):2177-85
The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ.
Habbig S, Bartram MP, Sägmüller JG, Griessmann A, Franke M, Müller RU, Schwarz R, Hoehne M, Bergmann C, Tessmer C, Reinhardt HC, Burst V, Benzing T, Schermer B
Human molecular genetics 2012 Dec 15;21(26):5528-38
Human molecular genetics 2012 Dec 15;21(26):5528-38
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Supportive validation
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- GeneTex (provider)
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- Experimental details
- Sample (30 ug of whole cell lysate) A: 293T B: A431 (GTX27909) C: H1299 7.5% SDS PAGE GTX112027 diluted at 1:1000