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- Validations
- Western blot [1]
- Immunohistochemistry [6]
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- Product number
- PA5-53647 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- TREML1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: APVGSSILVQ CHYRLQDVKA QKVWCRFLPE GCQPLVSSAV DRRAPAGRRT FLTDLGGGLL QVEMVTLQEE DAGEYGCMVD GARGPQILHR VSLNILPPEE EEETHKIGSL AENAFSDPAG SANPLEPSQD Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 25%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P, HCA Lung Biological Network, Deutsche COVID-19 Omics Initiative (DeCOI)
Immunity 2020 Dec 15;53(6):1296-1314.e9
Immunity 2020 Dec 15;53(6):1296-1314.e9
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of TREML1 in control (vector only transfected HEK293T lysate) and TREML1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a TREML1 Polyclonal Antibody (Product # PA5-53647).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of TREML1 in human kidney using TREML1 Polyclonal Antibody (Product # PA5-53647).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of TREML1 in human testis using TREML1 Polyclonal Antibody (Product # PA5-53647).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of TREML1 in human bone marrow shows strong positivity in megakaryocytes. Samples were probed using a TREML1 Polyclonal Antibody (Product # PA5-53647).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of TREML1 in human bone marrow and colon tissues using TREML1 Polyclonal Antibody (Product # PA5-53647). Corresponding TREML1 RNA-seq data are presented for the same tissues.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of TREML1 in human bone marrow, colon, kidney and testis using TREML1 Polyclonal Antibody (Product # PA5-53647) (A) shows similar protein distribution across tissues to an independent TREML1 Polyclonal Antibody (B).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of TREML1 in human colon using TREML1 Polyclonal Antibody (Product # PA5-53647) shows low expression as expected.
