Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 24822-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ATXN2L antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATXN2L antibody (Cat. #24822-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation.
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
Circadian clocks are modulated by compartmentalized oscillating translation.
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling.
Mid-Gestation lethality of Atxn2l-Ablated Mice.
ATXN2L upregulated by epidermal growth factor promotes gastric cancer cell invasiveness and oxaliplatin resistance.
Wang C, Terrigno M, Li J, Distler T, Pandya NJ, Ebeling M, Tyanova S, Hoozemans JJM, Dijkstra AA, Fuchs L, Xiang S, Bonni A, Grüninger F, Jagasia R
Neuron 2023 Sep 6;111(17):2660-2674.e9
Neuron 2023 Sep 6;111(17):2660-2674.e9
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
Pintacuda G, Hsu YH, Tsafou K, Li KW, Martín JM, Riseman J, Biagini JC, Ching JKT, Mena D, Gonzalez-Lozano MA, Egri SB, Jaffe J, Smit AB, Fornelos N, Eggan KC, Lage K
Cell genomics 2023 Mar 8;3(3):100250
Cell genomics 2023 Mar 8;3(3):100250
Circadian clocks are modulated by compartmentalized oscillating translation.
Zhuang Y, Li Z, Xiong S, Sun C, Li B, Wu SA, Lyu J, Shi X, Yang L, Chen Y, Bao Z, Li X, Sun C, Chen Y, Deng H, Li T, Wu Q, Qi L, Huang Y, Yang X, Lin Y
Cell 2023 Jul 20;186(15):3245-3260.e23
Cell 2023 Jul 20;186(15):3245-3260.e23
Jatrorrhizine ameliorates Schwann cell myelination via inhibiting HDAC3 ability to recruit Atxn2l for regulating the NRG1-ErbB2-PI3K-AKT pathway in diabetic peripheral neuropathy mice.
Gong X, Gui Z, Ye X, Li X
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Phytotherapy research : PTR 2023 Feb;37(2):645-657
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.
Cui Q, Bi H, Lv Z, Wu Q, Hua J, Gu B, Huo C, Tang M, Chen Y, Chen C, Chen S, Zhang X, Wu Z, Lao Z, Sheng N, Shen C, Zhang Y, Wu ZY, Jin Z, Yang P, Liu H, Li J, Bai G
Cell 2023 Feb 16;186(4):803-820.e25
Cell 2023 Feb 16;186(4):803-820.e25
Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling.
Araya LE, Soni IV, Hardy JA, Julien O
ACS chemical biology 2021 Nov 19;16(11):2280-2296
ACS chemical biology 2021 Nov 19;16(11):2280-2296
Mid-Gestation lethality of Atxn2l-Ablated Mice.
Key J, Harter PN, Sen NE, Gradhand E, Auburger G, Gispert S
International journal of molecular sciences 2020 Jul 20;21(14)
International journal of molecular sciences 2020 Jul 20;21(14)
ATXN2L upregulated by epidermal growth factor promotes gastric cancer cell invasiveness and oxaliplatin resistance.
Lin L, Li X, Pan C, Lin W, Shao R, Liu Y, Zhang J, Luo Y, Qian K, Shi M, Bin J, Liao Y, Liao W
Cell death & disease 2019 Feb 20;10(3):173
Cell death & disease 2019 Feb 20;10(3):173
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATXN2L antibody from Proteintech is a rabbit polyab antibody to a fusion protein of human ATXN2L. This antibody recognizes human antigen. The ATXN2L antibody has been validated for the following applications: ELISA, WB analysis.