Antibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
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- Product number
- ABIN954524 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1.
Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells.
Regulation of FGF1 gene promoter through transcription factor RFX1.
The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation.
Purvis TL, Hearn T, Spalluto C, Knorz VJ, Hanley KP, Sanchez-Elsner T, Hanley NA, Wilson DI
Gene 2010 Jul 15;460(1-2):20-9
Gene 2010 Jul 15;460(1-2):20-9
Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells.
Zhao M, Sun Y, Gao F, Wu X, Tang J, Yin H, Luo Y, Richardson B, Lu Q
Journal of autoimmunity 2010 Aug;35(1):58-69
Journal of autoimmunity 2010 Aug;35(1):58-69
Regulation of FGF1 gene promoter through transcription factor RFX1.
Hsu YC, Liao WC, Kao CY, Chiu IM
The Journal of biological chemistry 2010 Apr 30;285(18):13885-95
The Journal of biological chemistry 2010 Apr 30;285(18):13885-95
The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation.
Seguín-Estévez Q, De Palma R, Krawczyk M, Leimgruber E, Villard J, Picard C, Tagliamacco A, Abbate G, Gorski J, Nocera A, Reith W
Journal of immunology (Baltimore, Md. : 1950) 2009 Aug 15;183(4):2545-53
Journal of immunology (Baltimore, Md. : 1950) 2009 Aug 15;183(4):2545-53
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- Western blot analysis of RFX1 Antibody (C-term) Cat.-No AP53642PU-N in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the RFX1 antibody detected the RFX1 protein (arrow).