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- Antibody Data
- Antigen structure
- References [38]
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- Immunocytochemistry [3]
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- Product number
- ADI-SPA-895-J - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-SPA-895-J, RRID:AB_11180392
- Product name
- HO 1, pAb
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Protein A affinity purified. Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Submitted references Protective effects of monomethyl fumarate at the inflamed blood-brain barrier.
Cerebroprotection of flavanol (-)-epicatechin after traumatic brain injury via Nrf2-dependent and -independent pathways.
Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm.
Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury.
Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.
Hemoglobin induces monocyte recruitment and CD163-macrophage polarization in abdominal aortic aneurysm.
CO Induces Nrf2-Dependent Heme Oxygenase-1 Transcription by Cooperating with Sp1 and c-Jun in Rat Brain Astrocytes.
Cytoprotective responses in HaCaT keratinocytes exposed to high doses of curcumin.
Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice.
Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats.
Neurochemical phenotype of cytoglobin-expressing neurons in the rat hippocampus.
Systemic hemin therapy attenuates blood-brain barrier disruption after intracerebral hemorrhage.
Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice.
Preventive effect of agaro-oligosaccharides on non-steroidal anti-inflammatory drug-induced small intestinal injury in mice.
NRF2 immunolocalization in human breast cancer patients as a prognostic factor.
Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes.
Pleural mesothelial cell differentiation and invasion in fibrogenic lung injury.
Crucial role of heme oxygenase-1 on the sensitivity of cholangiocarcinoma cells to chemotherapeutic agents.
Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice.
Increased production of superoxide anion contributes to dysfunction of the arteriovenous fistula.
Enhanced expression of heme oxygenase-1 and carbon monoxide excitatory effects in oxytocin and vasopressin neurones during water deprivation.
Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula.
Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions.
Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia.
Induction of heme oxygenase-1 is a beneficial response in a murine model of venous thrombosis.
Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1.
Role of heme oxygenase-1 protein in the neuroprotective effects of cyclopentenone prostaglandin derivatives under oxidative stress.
Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress.
Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II.
Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response.
Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease.
Induction of heme oxygenase-1 modulates cis-aconitase activity in lens epithelial cells.
Heme oxygenase: recent advances in understanding its regulation and role.
Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis.
Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver.
Carbon monoxide formation in the ductus arteriosus in the lamb: implications for the regulation of muscle tone.
Expression of heme oxygenase-1 (HSP32) in human prostate: normal, hyperplastic, and tumor tissue distribution.
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Lim JL, van der Pol SM, Di Dio F, van Het Hof B, Kooij G, de Vries HE, van Horssen J
Microvascular research 2016 May;105:61-9
Microvascular research 2016 May;105:61-9
Cerebroprotection of flavanol (-)-epicatechin after traumatic brain injury via Nrf2-dependent and -independent pathways.
Cheng T, Wang W, Li Q, Han X, Xing J, Qi C, Lan X, Wan J, Potts A, Guan F, Wang J
Free radical biology & medicine 2016 Mar;92:15-28
Free radical biology & medicine 2016 Mar;92:15-28
Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm.
Barone E, Di Domenico F, Cassano T, Arena A, Tramutola A, Lavecchia MA, Coccia R, Butterfield DA, Perluigi M
Free radical biology & medicine 2016 Feb;91:127-42
Free radical biology & medicine 2016 Feb;91:127-42
Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury.
Lim SW, Jin L, Piao SG, Chung BH, Yang CW
Laboratory investigation; a journal of technical methods and pathology 2015 Oct;95(10):1174-85
Laboratory investigation; a journal of technical methods and pathology 2015 Oct;95(10):1174-85
Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.
Cao M, Onyango EO, Williams CR, Royce DB, Gribble GW, Sporn MB, Liby KT
Pharmacological research 2015 Oct;100:135-47
Pharmacological research 2015 Oct;100:135-47
Hemoglobin induces monocyte recruitment and CD163-macrophage polarization in abdominal aortic aneurysm.
Rubio-Navarro A, Amaro Villalobos JM, Lindholt JS, Buendía I, Egido J, Blanco-Colio LM, Samaniego R, Meilhac O, Michel JB, Martín-Ventura JL, Moreno JA
International journal of cardiology 2015 Dec 15;201:66-78
International journal of cardiology 2015 Dec 15;201:66-78
CO Induces Nrf2-Dependent Heme Oxygenase-1 Transcription by Cooperating with Sp1 and c-Jun in Rat Brain Astrocytes.
Chi PL, Lin CC, Chen YW, Hsiao LD, Yang CM
Molecular neurobiology 2015 Aug;52(1):277-92
Molecular neurobiology 2015 Aug;52(1):277-92
Cytoprotective responses in HaCaT keratinocytes exposed to high doses of curcumin.
Lundvig DM, Pennings SW, Brouwer KM, Mtaya-Mlangwa M, Mugonzibwa E, Kuijpers-Jagtman AM, Wagener FA, Von den Hoff JW
Experimental cell research 2015 Aug 15;336(2):298-307
Experimental cell research 2015 Aug 15;336(2):298-307
Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice.
Ghanem CI, Rudraiah S, Bataille AM, Vigo MB, Goedken MJ, Manautou JE
Biochemical pharmacology 2015 Apr 1;94(3):203-11
Biochemical pharmacology 2015 Apr 1;94(3):203-11
Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats.
Kobayashi M, Hoshinaga Y, Miura N, Tokuda Y, Shigeoka S, Murai A, Horio F
Bioscience, biotechnology, and biochemistry 2014;78(6):1060-6
Bioscience, biotechnology, and biochemistry 2014;78(6):1060-6
Neurochemical phenotype of cytoglobin-expressing neurons in the rat hippocampus.
Hundahl CA, Fahrenkrug J, Hannibal J
Biomedical reports 2014 Sep;2(5):620-627
Biomedical reports 2014 Sep;2(5):620-627
Systemic hemin therapy attenuates blood-brain barrier disruption after intracerebral hemorrhage.
Lu X, Chen-Roetling J, Regan RF
Neurobiology of disease 2014 Oct;70:245-51
Neurobiology of disease 2014 Oct;70:245-51
Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice.
Allwood MA, Kinobe RT, Ballantyne L, Romanova N, Melo LG, Ward CA, Brunt KR, Simpson JA
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2014 Jul-Aug;23(4):231-7
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2014 Jul-Aug;23(4):231-7
Preventive effect of agaro-oligosaccharides on non-steroidal anti-inflammatory drug-induced small intestinal injury in mice.
Higashimura Y, Naito Y, Takagi T, Tanimura Y, Mizushima K, Harusato A, Fukui A, Yoriki H, Handa O, Ohnogi H, Yoshikawa T
Journal of gastroenterology and hepatology 2014 Feb;29(2):310-7
Journal of gastroenterology and hepatology 2014 Feb;29(2):310-7
NRF2 immunolocalization in human breast cancer patients as a prognostic factor.
Onodera Y, Motohashi H, Takagi K, Miki Y, Shibahara Y, Watanabe M, Ishida T, Hirakawa H, Sasano H, Yamamoto M, Suzuki T
Endocrine-related cancer 2014 Apr;21(2):241-52
Endocrine-related cancer 2014 Apr;21(2):241-52
Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes.
Funakoshi-Hirose I, Aki T, Unuma K, Funakoshi T, Noritake K, Uemura K
Toxicology 2013 Oct 4;312:74-82
Toxicology 2013 Oct 4;312:74-82
Pleural mesothelial cell differentiation and invasion in fibrogenic lung injury.
Zolak JS, Jagirdar R, Surolia R, Karki S, Oliva O, Hock T, Guroji P, Ding Q, Liu RM, Bolisetty S, Agarwal A, Thannickal VJ, Antony VB
The American journal of pathology 2013 Apr;182(4):1239-47
The American journal of pathology 2013 Apr;182(4):1239-47
Crucial role of heme oxygenase-1 on the sensitivity of cholangiocarcinoma cells to chemotherapeutic agents.
Kongpetch S, Kukongviriyapan V, Prawan A, Senggunprai L, Kukongviriyapan U, Buranrat B
PloS one 2012;7(4):e34994
PloS one 2012;7(4):e34994
Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice.
Cummins NW, Weaver EA, May SM, Croatt AJ, Foreman O, Kennedy RB, Poland GA, Barry MA, Nath KA, Badley AD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Jul;26(7):2911-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Jul;26(7):2911-8
Increased production of superoxide anion contributes to dysfunction of the arteriovenous fistula.
Tsapenko MV, d'Uscio LV, Grande JP, Croatt AJ, Hernandez MC, Ackerman AW, Katusic ZS, Nath KA
American journal of physiology. Renal physiology 2012 Dec 15;303(12):F1601-7
American journal of physiology. Renal physiology 2012 Dec 15;303(12):F1601-7
Enhanced expression of heme oxygenase-1 and carbon monoxide excitatory effects in oxytocin and vasopressin neurones during water deprivation.
Reis WL, Biancardi VC, Son S, Antunes-Rodrigues J, Stern JE
Journal of neuroendocrinology 2012 Apr;24(4):653-63
Journal of neuroendocrinology 2012 Apr;24(4):653-63
Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula.
Kang L, Yamada S, Hernandez MC, Croatt AJ, Grande JP, Juncos JP, Vercellotti GM, Hebbel RP, Katusic ZS, Terzic A, Nath KA
American journal of physiology. Renal physiology 2011 Oct;301(4):F845-51
American journal of physiology. Renal physiology 2011 Oct;301(4):F845-51
Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions.
Ueda K, Ueyama T, Yoshida K, Kimura H, Ito T, Shimizu Y, Oka M, Tsuruo Y, Ichinose M
American journal of physiology. Gastrointestinal and liver physiology 2008 Sep;295(3):G460-9
American journal of physiology. Gastrointestinal and liver physiology 2008 Sep;295(3):G460-9
Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia.
Fervenza FC, Croatt AJ, Bittar CM, Rosenthal DW, Lager DJ, Leung N, Zeldenrust SR, Nath KA
American journal of kidney diseases : the official journal of the National Kidney Foundation 2008 Nov;52(5):972-7
American journal of kidney diseases : the official journal of the National Kidney Foundation 2008 Nov;52(5):972-7
Induction of heme oxygenase-1 is a beneficial response in a murine model of venous thrombosis.
Tracz MJ, Juncos JP, Grande JP, Croatt AJ, Ackerman AW, Katusic ZS, Nath KA
The American journal of pathology 2008 Dec;173(6):1882-90
The American journal of pathology 2008 Dec;173(6):1882-90
Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1.
Lad L, Schuller DJ, Shimizu H, Friedman J, Li H, Ortiz de Montellano PR, Poulos TL
The Journal of biological chemistry 2003 Mar 7;278(10):7834-43
The Journal of biological chemistry 2003 Mar 7;278(10):7834-43
Role of heme oxygenase-1 protein in the neuroprotective effects of cyclopentenone prostaglandin derivatives under oxidative stress.
Satoh T, Baba M, Nakatsuka D, Ishikawa Y, Aburatani H, Furuta K, Ishikawa T, Hatanaka H, Suzuki M, Watanabe Y
The European journal of neuroscience 2003 Jun;17(11):2249-55
The European journal of neuroscience 2003 Jun;17(11):2249-55
Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress.
Fonseca AM, Pereira CF, Porto G, Arosa FA
Free radical biology & medicine 2003 Dec 1;35(11):1404-16
Free radical biology & medicine 2003 Dec 1;35(11):1404-16
Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II.
Ishizaka N, Aizawa T, Ohno M, Usui Si S, Mori I, Tang SS, Ingelfinger JR, Kimura S, Nagai R
Hypertension 2002 Jan;39(1):122-8
Hypertension 2002 Jan;39(1):122-8
Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response.
Chang SH, Barbosa-Tessmann I, Chen C, Kilberg MS, Agarwal A
The Journal of biological chemistry 2002 Jan 18;277(3):1933-40
The Journal of biological chemistry 2002 Jan 18;277(3):1933-40
Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease.
Nath KA, Grande JP, Haggard JJ, Croatt AJ, Katusic ZS, Solovey A, Hebbel RP
The American journal of pathology 2001 Mar;158(3):893-903
The American journal of pathology 2001 Mar;158(3):893-903
Induction of heme oxygenase-1 modulates cis-aconitase activity in lens epithelial cells.
Rzymkiewicz DM, Reddan JR, Andley UP
Biochemical and biophysical research communications 2000 Apr 2;270(1):324-8
Biochemical and biophysical research communications 2000 Apr 2;270(1):324-8
Heme oxygenase: recent advances in understanding its regulation and role.
Elbirt KK, Bonkovsky HL
Proceedings of the Association of American Physicians 1999 Sep-Oct;111(5):438-47
Proceedings of the Association of American Physicians 1999 Sep-Oct;111(5):438-47
Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis.
Foresti R, Sarathchandra P, Clark JE, Green CJ, Motterlini R
The Biochemical journal 1999 May 1;339 ( Pt 3):729-36
The Biochemical journal 1999 May 1;339 ( Pt 3):729-36
Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver.
Bauer I, Wanner GA, Rensing H, Alte C, Miescher EA, Wolf B, Pannen BH, Clemens MG, Bauer M
Hepatology (Baltimore, Md.) 1998 Mar;27(3):829-38
Hepatology (Baltimore, Md.) 1998 Mar;27(3):829-38
Carbon monoxide formation in the ductus arteriosus in the lamb: implications for the regulation of muscle tone.
Coceani F, Kelsey L, Seidlitz E, Marks GS, McLaughlin BE, Vreman HJ, Stevenson DK, Rabinovitch M, Ackerley C
British journal of pharmacology 1997 Feb;120(4):599-608
British journal of pharmacology 1997 Feb;120(4):599-608
Expression of heme oxygenase-1 (HSP32) in human prostate: normal, hyperplastic, and tumor tissue distribution.
Maines MD, Abrahamsson PA
Urology 1996 May;47(5):727-33
Urology 1996 May;47(5):727-33
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Smith MA, Kutty RK, Richey PL, Yan SD, Stern D, Chader GJ, Wiggert B, Petersen RB, Perry G
The American journal of pathology 1994 Jul;145(1):42-7
The American journal of pathology 1994 Jul;145(1):42-7
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of HO-1 pAb: Lane 1: MW Marker, Lane 2: HO-1 (rat), Recombinant Protein (Prod. No. ADI-SPP-730) , Lane 3: Human Liver Microsomes, Lane 4: Mouse Liver Microsomes, Lane 5: Rat Liver Microsomes, Lane 6: Canine Liver Microsomes.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of human spleen tissue stained with HO-1, pAb at 10µg/ml.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of Alzheimer's diseased section stained with HO-1 (Hsp32) pAb.
