Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR02367G - Provider product page
- Provider
- Leading Biology
- Product name
- IER3 / IEX-1 Antibody (Internal)
- Antibody type
- Polyclonal
- Description
- May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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