Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11661-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11661-1-AP, RRID:AB_2180392
- Product name
- RRM2 antibody
- Antibody type
- Polyclonal
- Description
- RRM2 antibody (Cat. #11661-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RRM2 promotes the proliferation of chicken myoblasts, inhibits their differentiation and muscle regeneration.
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy.
RRM2‑mediated Wnt/β‑catenin signaling pathway activation in lung adenocarcinoma: A potential prognostic biomarker.
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC.
lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.
Novel Prognostic Signatures of Hepatocellular Carcinoma Based on Metabolic Pathway Phenotypes.
Integrated multi-omics approach revealed cellular senescence landscape.
Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.
A Novel Ferroptosis-Based Molecular Signature Associated with Biochemical Recurrence-Free Survival and Tumor Immune Microenvironment of Prostate Cancer.
The High Expression of RRM2 Can Predict the Malignant Transformation of Endometriosis.
A novel four-gene of iron metabolism-related and methylated for prognosis prediction of hepatocellular carcinoma.
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Potential tumor‑suppressive role of microRNA‑99a‑3p in sunitinib‑resistant renal cell carcinoma cells through the regulation of RRM2.
Inhibition of HIV early replication by the p53 and its downstream gene p21.
Long-term HIV-1 infection induces an antiviral state in primary macrophages.
Chen B, Zhang Y, Niu Y, Wang Y, Liu Y, Ji H, Han R, Tian Y, Liu X, Kang X, Li Z
Poultry science 2024 Mar;103(3):103407
Poultry science 2024 Mar;103(3):103407
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy.
Wang S, Wang R, Hu D, Zhang C, Cao P, Huang J
NPJ precision oncology 2024 Feb 26;8(1):49
NPJ precision oncology 2024 Feb 26;8(1):49
RRM2‑mediated Wnt/β‑catenin signaling pathway activation in lung adenocarcinoma: A potential prognostic biomarker.
Jiang Y, Hu X, Pang M, Huang Y, Ren B, He L, Jiang L
Oncology letters 2023 Oct;26(4):417
Oncology letters 2023 Oct;26(4):417
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
Tan J, Wang W, Liu X, Xu J, Che Y, Liu Y, Hu J, Hu L, Li J, Zhou Q
Communications biology 2023 Jun 5;6(1):606
Communications biology 2023 Jun 5;6(1):606
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC.
Zhang X, Sun J, Zhang P, Wen T, Wang R, Liang L, Yang Z, Li J, Zhang J, Che B, Feng X, Liu X, Han H, Yan X
Molecular therapy. Nucleic acids 2023 Jun 13;32:343-358
Molecular therapy. Nucleic acids 2023 Jun 13;32:343-358
lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.
Liang G, Zeng M, Gao M, Xing W, Jin X, Wang Q, Deng L, Ou H, He Z
Oxidative medicine and cellular longevity 2022;2022:9369035
Oxidative medicine and cellular longevity 2022;2022:9369035
Novel Prognostic Signatures of Hepatocellular Carcinoma Based on Metabolic Pathway Phenotypes.
Ye T, Lin L, Cao L, Huang W, Wei S, Shan Y, Zhang Z
Frontiers in oncology 2022;12:863266
Frontiers in oncology 2022;12:863266
Integrated multi-omics approach revealed cellular senescence landscape.
Song Q, Hou Y, Zhang Y, Liu J, Wang Y, Fu J, Zhang C, Cao M, Cui Y, Zhang X, Wang X, Zhang J, Liu C, Zhang Y, Wang P
Nucleic acids research 2022 Oct 28;50(19):10947-10963
Nucleic acids research 2022 Oct 28;50(19):10947-10963
Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.
Li Y, Cen Y, Fang Y, Tang S, Li S, Ren Y, Zhang H, Lu W, Xu J
ACS nano 2022 Aug 23;16(8):12786-12800
ACS nano 2022 Aug 23;16(8):12786-12800
A Novel Ferroptosis-Based Molecular Signature Associated with Biochemical Recurrence-Free Survival and Tumor Immune Microenvironment of Prostate Cancer.
Ke ZB, You Q, Sun JB, Zhu JM, Li XD, Chen DN, Su L, Zheng QS, Wei Y, Xue XY, Xu N
Frontiers in cell and developmental biology 2021;9:774625
Frontiers in cell and developmental biology 2021;9:774625
The High Expression of RRM2 Can Predict the Malignant Transformation of Endometriosis.
Yang B, Wang T, Li N, Zhang W, Hu Y
Advances in therapy 2021 Oct;38(10):5178-5190
Advances in therapy 2021 Oct;38(10):5178-5190
A novel four-gene of iron metabolism-related and methylated for prognosis prediction of hepatocellular carcinoma.
Shen H, Wu H, Sun F, Qi J, Zhu Q
Bioengineered 2021 Dec;12(1):240-251
Bioengineered 2021 Dec;12(1):240-251
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Wu Z, Zhan Y, Wang L, Tong J, Zhang L, Lin M, Jin X, Jiang L, Lou Y, Qiu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Potential tumor‑suppressive role of microRNA‑99a‑3p in sunitinib‑resistant renal cell carcinoma cells through the regulation of RRM2.
Osako Y, Yoshino H, Sakaguchi T, Sugita S, Yonemori M, Nakagawa M, Enokida H
International journal of oncology 2019 May;54(5):1759-1770
International journal of oncology 2019 May;54(5):1759-1770
Inhibition of HIV early replication by the p53 and its downstream gene p21.
Shi B, Sharifi HJ, DiGrigoli S, Kinnetz M, Mellon K, Hu W, de Noronha CMC
Virology journal 2018 Mar 27;15(1):53
Virology journal 2018 Mar 27;15(1):53
Long-term HIV-1 infection induces an antiviral state in primary macrophages.
Pujantell M, Badia R, Ramirez C, Puig T, Clotet B, Ballana E, Esté JA, Riveira-Muñoz E
Antiviral research 2016 Sep;133:145-55
Antiviral research 2016 Sep;133:145-55
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 11661-1-AP(RRM2 antibody) at dilution of 1:200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RRM2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RRM2. This antibody recognizes human,mouse,rat antigen. The RRM2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.