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- Antibody Data
- Antigen structure
- References [7]
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- Product number
- 67006-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- RRM2 antibody
- Antibody type
- Monoclonal
- Description
- RRM2 antibody (Cat. #67006-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2A9A7
- Vial size
- 20ul, 150ul
Submitted references RRM2/GCH1 signaling decreased cisplatin sensitivity in cervical cancer by modulating the ferroptosis process.
CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.
DEAD/H-box RNA helicase 10 promotes pancreatic cancer cell proliferation via ribonucleotide reductase M2.
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
RRM2 promotes liver metastasis of pancreatic cancer by stabilizing YBX1 and activating the TGF-beta pathway.
Therapeutic targeting of thioredoxin reductase 1 causes ferroptosis while potentiating anti-PD-1 efficacy in head and neck cancer.
The SNHG16/miR-30a axis promotes breast cancer cell proliferation and invasion by regulating RRM2.
Zhao J, Wang L, Shao N, Qu Y, Chen W, Sun H
Histology and histopathology 2026 Mar 6;:25056
Histology and histopathology 2026 Mar 6;:25056
CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.
Feng L, Zou X, Tang L, Yuan Y, He T, Su B, Tang Y, Wang J, Liu K, Li J
Frontiers in pharmacology 2025;16:1563869
Frontiers in pharmacology 2025;16:1563869
DEAD/H-box RNA helicase 10 promotes pancreatic cancer cell proliferation via ribonucleotide reductase M2.
Qiu ZS, Wang XC, Ma JC, Zhu CL, Hu YL, Da MX
World journal of gastrointestinal oncology 2025 Sep 15;17(9):108672
World journal of gastrointestinal oncology 2025 Sep 15;17(9):108672
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
Gao H, Shi L, Liu J, Zhao Y, Du F, He Y, Yang X, Song N, Wen J, Zheng G
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
RRM2 promotes liver metastasis of pancreatic cancer by stabilizing YBX1 and activating the TGF-beta pathway.
Du Z, Zhang Q, Xiang X, Li W, Yang Q, Yu H, Liu T
iScience 2024 Oct 18;27(10):110864
iScience 2024 Oct 18;27(10):110864
Therapeutic targeting of thioredoxin reductase 1 causes ferroptosis while potentiating anti-PD-1 efficacy in head and neck cancer.
Hsieh MS, Ling HH, Setiawan SA, Hardianti MS, Fong IH, Yeh CT, Chen JH
Chemico-biological interactions 2024 May 25;395:111004
Chemico-biological interactions 2024 May 25;395:111004
The SNHG16/miR-30a axis promotes breast cancer cell proliferation and invasion by regulating RRM2.
Du SM
Neoplasma 2020 May;67(3):567-575
Neoplasma 2020 May;67(3):567-575
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