CABT-BL7611

antibody from Creative Diagnostics

Targeting: HLA-DQB1 CELIAC1, HLA-DQB, IDDM1

No application information provided.

Antibody Data

Product number

CABT-BL7611

Provider

Creative Diagnostics

Product name

Anti-HLA-DQB1 Monoclonal antibody, clone TL20 [FITC]

Antibody type

Monoclonal

Description

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide