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- Antigen structure
- References [6]
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- Western blot [1]
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- Product number
- 21158-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21158-1-AP, RRID:AB_2752255
- Product name
- GIYD2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GIYD2 antibody (Cat. #21158-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SLX1 silencing overcomes Olaparib resistance in metastatic castration-resistant prostate cancer by disrupting SLX4-mediated DNA repair complexes.
Molecular basis of XPF-ERCC1 targeting to SLX4-dependent DNA repair pathways.
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.
ATR limits Rad18-mediated PCNA monoubiquitination to preserve replication fork and telomerase-independent telomere stability.
Break-induced replication promotes fragile telomere formation.
SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.
Zhao X, Feng S, Nitie X, Muluo S, Lei Y
Cancer biology & therapy 2025 Dec;26(1):2545062
Cancer biology & therapy 2025 Dec;26(1):2545062
Molecular basis of XPF-ERCC1 targeting to SLX4-dependent DNA repair pathways.
Feng J, Martin PR, Kowalski S, Lecot M, Cronin NB, Matthews-Palmer T, Niedzwiedz W, Greber BJ
Nature communications 2025 Dec 16;17(1):522
Nature communications 2025 Dec 16;17(1):522
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.
Tsukada K, Jones SE, Bannister J, Durin MA, Vendrell I, Fawkes M, Fischer R, Kessler BM, Chapman JR, Blackford AN
Molecular cell 2024 Feb 15;84(4):640-658.e10
Molecular cell 2024 Feb 15;84(4):640-658.e10
ATR limits Rad18-mediated PCNA monoubiquitination to preserve replication fork and telomerase-independent telomere stability.
Chen S, Pan C, Huang J, Liu T
The EMBO journal 2024 Apr;43(7):1301-1324
The EMBO journal 2024 Apr;43(7):1301-1324
Break-induced replication promotes fragile telomere formation.
Yang Z, Takai KK, Lovejoy CA, de Lange T
Genes & development 2020 Oct 1;34(19-20):1392-1405
Genes & development 2020 Oct 1;34(19-20):1392-1405
SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.
Panier S, Maric M, Hewitt G, Mason-Osann E, Gali H, Dai A, Labadorf A, Guervilly JH, Ruis P, Segura-Bayona S, Belan O, Marzec P, Gaillard PL, Flynn RL, Boulton SJ
Molecular cell 2019 Oct 3;76(1):27-43.e11
Molecular cell 2019 Oct 3;76(1):27-43.e11
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GIYD2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GIYD2. This antibody recognizes human, mouse antigen. The GIYD2 antibody has been validated for the following applications: ELISA, WB analysis.
