DPABH-18159

antibody from Creative Diagnostics

Targeting: RALA RAL

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DPABH-18159

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-18159, RRID:AB_2526279

Product name

Rabbit Anti-Human RALA Polyclonal Antibody

Antibody type

Polyclonal

Description

Multifuntional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Concentration

Lot specific

Storage

Store at -20°C, and avoid repeat freeze-thaw cycles.