Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 55100-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55100-1-AP, RRID:AB_10858486
- Product name
- SPI1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SPI1 antibody (Cat. #55100-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FBXO22 targets ubiquitination and degradation of c-Cbl in leukemia.
Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis.
S100A9 inhibition ameliorates HFpEF by modulating mitochondrial fission and oxidative stress.
CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription.
Pentraxin 3 promotes microglial M2 polarization and excitatory synapse formation in the hippocampus in depression.
SPI1 Regulates Autophagy by Promoting ATG7 Transcription to Enhance Ferroptosis in Myocardial Ischemia/Reperfusion Injury.
Therapeutic targeting SPI1 in combination with erastin promotes ferroptosis in ccRCC.
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
An innovative immunotherapeutic strategy for rheumatoid arthritis: Selectively suppressing angiogenesis and osteoclast differentiation by fully human antibody targeting thymocyte antigen-1.
PU.1 negatively regulates tumorigenesis in non-small-cell lung cancer.
IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation.
Specific immunotherapy in combination with Clostridium butyricum inhibits allergic inflammation in the mouse intestine.
miR-199a-5p inhibits monocyte/macrophage differentiation by targeting the activin A type 1B receptor gene and finally reducing C/EBPα expression.
Li J, Ma L, Wang J, Xu W, Cheng Y, Zhang J, Cao H, Wang Y, Wang Z, Xu H, Li Y, Zhang Y
Scientific reports 2026 Feb 26;16(1)
Scientific reports 2026 Feb 26;16(1)
Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis.
Yu Y, Yu C, Dai S, Liu Y, Hu L, Lu W
Frontiers in genetics 2025;16:1617834
Frontiers in genetics 2025;16:1617834
S100A9 inhibition ameliorates HFpEF by modulating mitochondrial fission and oxidative stress.
Wang M, Ren B, Wu X, Guo J, Cao Y, Men L, Shi W, Zhang C, Lin L, Lv J, Li S, Huo S
International immunopharmacology 2025 Oct 10;163:115280
International immunopharmacology 2025 Oct 10;163:115280
CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription.
Miao K, Zhou J, Chen J
Hereditas 2025 Nov 26;162(1):233
Hereditas 2025 Nov 26;162(1):233
Pentraxin 3 promotes microglial M2 polarization and excitatory synapse formation in the hippocampus in depression.
Xu Y, Wang M, Wei H, Yu M, Li Y
International immunopharmacology 2025 Jan 27;146:113946
International immunopharmacology 2025 Jan 27;146:113946
SPI1 Regulates Autophagy by Promoting ATG7 Transcription to Enhance Ferroptosis in Myocardial Ischemia/Reperfusion Injury.
Li WL, Han X, Pan WL, Wang H, You DL, Chen XT, Wu X, Jin MM, Wang F
Journal of cellular biochemistry 2025 Dec;126(12):e70078
Journal of cellular biochemistry 2025 Dec;126(12):e70078
Therapeutic targeting SPI1 in combination with erastin promotes ferroptosis in ccRCC.
Xue W, Wu Z, Li J, Jin P, Zhu Y, Li Z, Wang Z, Li Z, Fei X
Communications biology 2025 Dec 10;8(1):1772
Communications biology 2025 Dec 10;8(1):1772
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
Zheng JH, Zhu YH, Yang J, Ji PX, Zhao RK, Duan ZH, Yao HF, Jia QY, Yin YF, Hu LP, Li Q, Jiang SH, Huo YM, Liu W, Sun YW, Liu DJ
Cell reports 2024 Aug 27;43(8):114633
Cell reports 2024 Aug 27;43(8):114633
An innovative immunotherapeutic strategy for rheumatoid arthritis: Selectively suppressing angiogenesis and osteoclast differentiation by fully human antibody targeting thymocyte antigen-1.
Hu X, Li M, Zhang Y, Sang K, Zhang Y, Li W, Liu B, Wan L, Du B, Qian J, Meng F, Fu Y, Dai M, Gao G, Ye H
Experimental cell research 2023 Mar 1;424(1):113490
Experimental cell research 2023 Mar 1;424(1):113490
PU.1 negatively regulates tumorigenesis in non-small-cell lung cancer.
Liu X, Xu M, Jia W, Duan Y, Ma J, Tai W
Medical oncology (Northwood, London, England) 2023 Jan 17;40(2):79
Medical oncology (Northwood, London, England) 2023 Jan 17;40(2):79
IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation.
Hu J, Gao N, Zhang Y, Chen X, Li J, Bian F, Chi W, Liu Z, de Paiva CS, Pflugfelder SC, Li DQ
Mucosal immunology 2020 Nov;13(6):919-930
Mucosal immunology 2020 Nov;13(6):919-930
Specific immunotherapy in combination with Clostridium butyricum inhibits allergic inflammation in the mouse intestine.
Shi Y, Xu LZ, Peng K, Wu W, Wu R, Liu ZQ, Yang G, Geng XR, Liu J, Liu ZG, Liu Z, Yang PC
Scientific reports 2015 Dec 2;5:17651
Scientific reports 2015 Dec 2;5:17651
miR-199a-5p inhibits monocyte/macrophage differentiation by targeting the activin A type 1B receptor gene and finally reducing C/EBPα expression.
Lin HS, Gong JN, Su R, Chen MT, Song L, Shen C, Wang F, Ma YN, Zhao HL, Yu J, Li WW, Huang LX, Xu XH, Zhang JW
Journal of leukocyte biology 2014 Dec;96(6):1023-35
Journal of leukocyte biology 2014 Dec;96(6):1023-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The SPI1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SPI1. This antibody recognizes human, mouse, rat antigen. The SPI1 antibody has been validated for the following applications: ELISA, WB analysis.