Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- HPA035166 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA035166, RRID:AB_10602709
- Product name
- Anti-METTL6
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human METTL6, Gene description: methyltransferase like 6, Alternative Gene Names: MGC24132, Validated applications: ICC, IHC, WB, Uniprot ID: Q8TCB7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules
METTL6 is a tRNA m 3 C methyltransferase that regulates pluripotency and tumor cell growth
Bolatkan A, Asada K, Kaneko S, Suvarna K, Ikawa N, Machino H, Komatsu M, Shiina S, Hamamoto R
International Journal of Oncology 2021;60(1)
International Journal of Oncology 2021;60(1)
METTL6 is a tRNA m 3 C methyltransferase that regulates pluripotency and tumor cell growth
Ignatova V, Kaiser S, Ho J, Bing X, Stolz P, Tan Y, Lee C, Gay F, Lastres P, Gerlini R, Rathkolb B, Aguilar-Pimentel A, Sanz-Moreno A, Klein-Rodewald T, Calzada-Wack J, Ibragimov E, Valenta M, Lukauskas S, Pavesi A, Marschall S, Leuchtenberger S, Fuchs H, Gailus-Durner V, de Angelis M, Bultmann S, Rando O, Guccione E, Kellner S, Schneider R
Science Advances 2020;6(35)
Science Advances 2020;6(35)
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and METTL6 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY407564).
- Sample type
- Human
- Protocol
- Protocol