Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 55224-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55224-1-AP, RRID:AB_11182714
- Product name
- HCN4 antibody
- Antibody type
- Polyclonal
- Description
- HCN4 antibody (Cat. #55224-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DNA methylation cooperates with H3K9me2 at HCN4 promoter to regulate the differentiation of bone marrow mesenchymal stem cells into pacemaker-like cells.
G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region.
A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish family.
Glucocorticoid Receptor/HCN4 Channels Interaction in Spinal Dorsal Horn Participates in the Regulation of Neuropathic Pain after Peripheral Nerve Injury in Rats.
Engineering of thick human functional myocardium via static stretching and electrical stimulation.
Sun X, Jin K, Ding X, Ruan Z, Xu P
PloS one 2023;18(8):e0289510
PloS one 2023;18(8):e0289510
G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region.
Xu P, Jin K, Zhou J, Gu J, Gu X, Dong L, Sun X
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish family.
Cámara-Checa A, Perin F, Rubio-Alarcón M, Dago M, Crespo-García T, Rapún J, Marín M, Cebrián J, Gómez R, Bermúdez-Jiménez F, Monserrat L, Tamargo J, Caballero R, Jiménez-Jáimez J, Delpón E
Proceedings of the National Academy of Sciences of the United States of America 2023 Dec 5;120(49):e2305135120
Proceedings of the National Academy of Sciences of the United States of America 2023 Dec 5;120(49):e2305135120
Glucocorticoid Receptor/HCN4 Channels Interaction in Spinal Dorsal Horn Participates in the Regulation of Neuropathic Pain after Peripheral Nerve Injury in Rats.
Zhengshuai L, Yan F, Jinglin L, Hua P, Chunmei W
Bulletin of experimental biology and medicine 2022 Sep;173(5):594-601
Bulletin of experimental biology and medicine 2022 Sep;173(5):594-601
Engineering of thick human functional myocardium via static stretching and electrical stimulation.
Pretorius D, Kahn-Krell AM, LaBarge WC, Lou X, Zhang J
iScience 2022 Mar 18;25(3):103824
iScience 2022 Mar 18;25(3):103824
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The HCN4 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human HCN4. This antibody recognizes human, mouse, rat antigen. The HCN4 antibody has been validated for the following applications: ELISA, WB analysis.