BS7939

antibody from Bioworld Technology, Inc
Targeting: TCF19 SC1
Provider product page for BS7939
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7939 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TCF19 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TCF19.
Description
TCF-19 (transcription factor 19), also known as SC1 or SC1-1, is a 345 amino acid protein that contains one FHA domain, a proline-rich domain and one PHD-type zinc finger. Localizing to the nucleus, TCF-19 is a growth regulated protein that is believed to function as a trans-activating factor with a role in the transcription of genes involved in the late stages of cell cycle progression (G1 to S transition or entry of cells into G2 and mitosis). TCF-19 is expressed preferentially in the G1-S phase of the cell cycle. The gene encoding TCF-19 localizes to a critical region on chromosome 6 that has been associated with psoriasis vulgaris, a disorder of the skin that is characterized by hyperproliferation of epidermal cells. This suggests that TCF-19, via its regulation of late cell cycle-specific genes, may play a role in the development of this disorder.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TCF19 protein structure - BS7939 shown in red.