Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16241-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16241-1-AP, RRID:AB_2145705
- Product name
- MRPL13 antibody
- Antibody type
- Polyclonal
- Description
- MRPL13 antibody (Cat. #16241-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dysregulation of human ClpP using small molecules with piperazine-based scaffold for diffuse intrinsic pontine glioma therapy validated by patient-derived tumor organoids.
MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6.
Deficiency of HSF4 Increases the Secretion of Small Extracellular Vesicles via Upregulation of Chaperone-Mediated Autophagy.
MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling.
A roadmap for ribosome assembly in human mitochondria.
Molecular Investigation of Mitochondrial RNA19 Role in the Pathogenesis of MELAS Disease.
MRPL13 Promotes Tumor Cell Proliferation, Migration and EMT Process in Breast Cancer Through the PI3K-AKT-mTOR Pathway.
Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses.
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
CLUH couples mitochondrial distribution to the energetic and metabolic status.
MPV17L2 is required for ribosome assembly in mitochondria.
Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis.
Miciaccia M, Armenise D, Baldelli OM, Liturri A, Mammone M, Graziano G, Contino M, Rizzo F, Polosa PL, Bruni F, Deligne C, Broutier L, Cavallaro G, Fortuna CG, Tolomeo A, Green C, Bonifazi A, Majaesic E, Barghash MM, Lee NPJ, Houry WA, Gratteri C, Talarico C, Filieri S, Micalizzi G, Donnarumma D, Dugo P, Mondello L, Sardanelli AM, Nazarian J, Ferorelli S, Perrone MG, Scilimati A
Research square 2026 Jan 14;
Research square 2026 Jan 14;
MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6.
Liu O, Hu Y, Wang S, Nie X, Wang Y, Fan X, Zeng K, Li X, Liu B, Lin B
Cell death & disease 2025 Aug 21;16(1):634
Cell death & disease 2025 Aug 21;16(1):634
Deficiency of HSF4 Increases the Secretion of Small Extracellular Vesicles via Upregulation of Chaperone-Mediated Autophagy.
Liu J, Liu X, Xie X, Si W, Zhang Y, Xue M, Peng X, Jiang M, Du S, Shao J, Mao Y, Zhang F, Hu Y
Journal of cellular biochemistry 2025 Apr;126(4):e70031
Journal of cellular biochemistry 2025 Apr;126(4):e70031
MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling.
Rigoni G, Calvo E, Glytsou C, Carro-Alvarellos M, Noguchi M, Semenzato M, Quirin C, Caicci F, Meneghetti N, Sturlese M, Ishihara T, Moro S, Rampazzo C, Ishihara N, Bezzo F, Salviati L, Vazquez J, Sales G, Romualdi C, Enriquez JA, Scorrano L, Soriano ME
Cell metabolism 2025 Apr 1;37(4):1024-1038.e8
Cell metabolism 2025 Apr 1;37(4):1024-1038.e8
A roadmap for ribosome assembly in human mitochondria.
Lavdovskaia E, Hanitsch E, Linden A, PaĊĦen M, Challa V, Horokhovskyi Y, Roetschke HP, Nadler F, Welp L, Steube E, Heinrichs M, Mai MM, Urlaub H, Liepe J, Richter-Dennerlein R
Nature structural & molecular biology 2024 Dec;31(12):1898-1908
Nature structural & molecular biology 2024 Dec;31(12):1898-1908
Molecular Investigation of Mitochondrial RNA19 Role in the Pathogenesis of MELAS Disease.
Loguercio Polosa P, Capriglia F, Bruni F
Life (Basel, Switzerland) 2023 Sep 3;13(9)
Life (Basel, Switzerland) 2023 Sep 3;13(9)
MRPL13 Promotes Tumor Cell Proliferation, Migration and EMT Process in Breast Cancer Through the PI3K-AKT-mTOR Pathway.
Cai M, Li H, Chen R, Zhou X
Cancer management and research 2021;13:2009-2024
Cancer management and research 2021;13:2009-2024
Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses.
Shi R, Feng Z, Zhang X
Genomics, proteomics & bioinformatics 2021 Oct;19(5):707-726
Genomics, proteomics & bioinformatics 2021 Oct;19(5):707-726
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
Lavdovskaia E, Kolander E, Steube E, Mai MM, Urlaub H, Richter-Dennerlein R
Nucleic acids research 2018 Sep 19;46(16):8471-8482
Nucleic acids research 2018 Sep 19;46(16):8471-8482
CLUH couples mitochondrial distribution to the energetic and metabolic status.
Wakim J, Goudenege D, Perrot R, Gueguen N, Desquiret-Dumas V, Chao de la Barca JM, Dalla Rosa I, Manero F, Le Mao M, Chupin S, Chevrollier A, Procaccio V, Bonneau D, Logan DC, Reynier P, Lenaers G, Khiati S
Journal of cell science 2017 Jun 1;130(11):1940-1951
Journal of cell science 2017 Jun 1;130(11):1940-1951
MPV17L2 is required for ribosome assembly in mitochondria.
Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EM, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A
Nucleic acids research 2014 Jul;42(13):8500-15
Nucleic acids research 2014 Jul;42(13):8500-15
Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis.
Surovtseva YV, Shadel GS
Nucleic acids research 2013 Feb 1;41(4):2479-88
Nucleic acids research 2013 Feb 1;41(4):2479-88
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 16241-1-AP(MRPL13 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 16241-1-AP(MRPL13 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The MRPL13 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MRPL13. This antibody recognizes human,mouse,rat, monkey antigen. The MRPL13 antibody has been validated for the following applications: ELISA, WB, IHC analysis.