orb385945

antibody from Biorbyt
Targeting: LGALS1 GBP
Provider product page for orb385945
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
orb385945 - Provider product page
Provider
Biorbyt
Product name
Galectin 1 Antibody / LGALS1
Antibody type
Monoclonal
Description
Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
GAL1/1831
Vial size
20 ug
Storage
Store the Galectin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
LGALS1 protein structure - orb385945 shown in red.