Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AFC-445CL - Provider product page
- Provider
- Creative Biolabs
- Product name
- Afuco? Anti-Human ITGB7 ADCC Recombinant Antibody, ADCC Enhanced
- Antibody type
- Monoclonal
- Description
- Anti-ITGB7 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco? platform. This is a humanized anti-human ¦Â7 monoclonal antibody currently in phase I in inflammatory bowel disease. It binds the ¦Â7 subunit of the integrins ¦Á4¦Â7 and ¦ÁE¦Â7, blocking interaction with their ligands. These integrins play key roles in immune cell homing to and retention in mucosal sites, and are associated with chronic inflammatory diseases of the gastrointestinal tract.
- Reactivity
- Human
- Storage
- Store at 4¡ãC for up to 3 months. For longer term storage aliquot into small volumes and store at -20¡ãC.
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