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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- ABIN151796 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Extra Spindle Poles Like 1 (ESPL1) (C-Term) antibody
- Antibody type
- Monoclonal
- Description
- Unpurified
- Reactivity
- Human
- Host
- Mouse
- Epitope
- C-Term
- Isotype
- IgG
- Antibody clone number
- XJ11-4D7
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Functional interaction between BubR1 and securin in an anaphase-promoting complex/cyclosomeCdc20-independent manner.
Regulation of the anaphase-promoting complex-separase cascade by transforming growth factor-beta modulates mitotic progression in bone marrow stromal cells.
Effect of separase depletion on ionizing radiation-induced cell cycle checkpoints and survival in human lung cancer cell lines.
Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.
Western blot screening for monoclonal antibodies against human separase.
Processing, localization, and requirement of human separase for normal anaphase progression.
Kim HS, Jeon YK, Ha GH, Park HY, Kim YJ, Shin HJ, Lee CG, Chung DH, Lee CW
Cancer research 2009 Jan 1;69(1):27-36
Cancer research 2009 Jan 1;69(1):27-36
Regulation of the anaphase-promoting complex-separase cascade by transforming growth factor-beta modulates mitotic progression in bone marrow stromal cells.
Fujita T, Epperly MW, Zou H, Greenberger JS, Wan Y
Molecular biology of the cell 2008 Dec;19(12):5446-55
Molecular biology of the cell 2008 Dec;19(12):5446-55
Effect of separase depletion on ionizing radiation-induced cell cycle checkpoints and survival in human lung cancer cell lines.
Sak A, Fegers I, Groneberg M, Stuschke M
Cell proliferation 2008 Aug;41(4):660-70
Cell proliferation 2008 Aug;41(4):660-70
Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.
Rubinek T, Chesnokova V, Wolf I, Wawrowsky K, Vlotides G, Melmed S
American journal of physiology. Cell physiology 2007 Sep;293(3):C1082-92
American journal of physiology. Cell physiology 2007 Sep;293(3):C1082-92
Western blot screening for monoclonal antibodies against human separase.
Chestukhin A, DeCaprio JA
Journal of immunological methods 2003 Mar 1;274(1-2):105-13
Journal of immunological methods 2003 Mar 1;274(1-2):105-13
Processing, localization, and requirement of human separase for normal anaphase progression.
Chestukhin A, Pfeffer C, Milligan S, DeCaprio JA, Pellman D
Proceedings of the National Academy of Sciences of the United States of America 2003 Apr 15;100(8):4574-9
Proceedings of the National Academy of Sciences of the United States of America 2003 Apr 15;100(8):4574-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Overlay [blue] of centrosomal staining in HeLa cells. Centrosomal staining of separase [yellow], using ABIN151796, and gamma tubulin [green] in mitotic-metaphase cells and nuclear staining of separase in pre-mitotic cells.
