HPA017319

antibody from Atlas Antibodies

Targeting: IFNLR1 CRF2/12, IFNLR, IL-28R1, IL28RA

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA017319

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA017319, RRID:AB_1851708

Product name

Anti-IFNLR1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human IFNLR1, Gene description: interferon, lambda receptor 1, Alternative Gene Names: CRF2/12, IFNLR, IL-28R1, IL28RA, Validated applications: IHC, Uniprot ID: Q8IU57, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infection

Tsai M, Osman W, Adair J, ElMergawy R, Chafin L, Johns F, Farkas D, Elhance A, Londino J, Mallampalli R
Journal of Biological Chemistry 2022;298(12):102698

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Macrophage Coordination of the Interferon Lambda Immune Response

Read S, Wijaya R, Ramezani-Moghadam M, Tay E, Schibeci S, Liddle C, Lam V, Yuen L, Douglas M, Booth D, George J, Ahlenstiel G
Frontiers in Immunology 2019;10

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Zinc is a potent and specific inhibitor of IFN-λ3 signalling

Read S, O’Connor K, Suppiah V, Ahlenstiel C, Obeid S, Cook K, Cunningham A, Douglas M, Hogg P, Booth D, George J, Ahlenstiel G
Nature Communications 2017;8(1)

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Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus

Zahn S, Rehkämper C, Kümmerer B, Ferring-Schmidt S, Bieber T, Tüting T, Wenzel J
Journal of Investigative Dermatology 2011;131(1):133-140