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- Antibody Data
- Antigen structure
- References [18]
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- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 12866-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- FBXO32 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FBXO32 antibody (Cat. #12866-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Down-regulated Smyd1 participated in the inhibition of myoblast differentiation induced by cigarette smoke extract.
The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy.
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Serum IL-35 levels is a new candidate biomarker of cancer-related cachexia in stage IV non-small cell lung cancer.
Differential Protein Metabolism and Regeneration in Gastrocnemius Muscles in High-fat Diet Fed Mice and Pre-hibernation Daurian Ground Squirrels: A Comparison between Pathological and Healthy Obesity.
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle.
Serum insulin-like growth factor binding protein 2 levels as biomarker for pancreatic ductal adenocarcinoma-associated malnutrition and muscle wasting.
Differential protein metabolism and regeneration in hypertrophic diaphragm and atrophic gastrocnemius muscles in hibernating Daurian ground squirrels.
Cyanidin-3-O-glucoside inhibits epithelial-to-mesenchymal transition, and migration and invasion of breast cancer cells by upregulating KLF4.
Different fuel regulation in two types of myofiber results in different antioxidant strategies in Daurian ground squirrels (Spermophilus dauricus) during hibernation.
Trichostatin A inhibits skeletal muscle atrophy induced by cigarette smoke exposure in mice.
Age-dependent effects of caloric restriction on mTOR and ubiquitin-proteasome pathways in skeletal muscles.
Suppression of protein degradation by leucine requires its conversion to β-hydroxy-β-methyl butyrate in C2C12 myotubes.
Beta-hydroxy beta-methyl butyrate decreases muscle protein degradation via increased Akt/FoxO3a signaling and mitochondrial biogenesis in weanling piglets after lipopolysaccharide challenge.
3F-Box protein 32 degrades ataxia telangiectasia and Rad3-related and regulates DNA damage response induced by gemcitabine in pancreatic cancer.
Spermidine-Activated Satellite Cells Are Associated with Hypoacetylation in ACVR2B and Smad3 Binding to Myogenic Genes in Mice.
Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response.
Li F, Xu M, Miao J, Hu N, Wang Y, Wang L
Toxicology letters 2023 Jul 1;383:98-111
Toxicology letters 2023 Jul 1;383:98-111
The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy.
Ito Y, Yamagata M, Yamamoto T, Hirasaka K, Nikawa T, Sato T
eLife 2023 Dec 15;12
eLife 2023 Dec 15;12
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Zou YY, Chen ZL, Sun CC, Yang D, Zhou ZQ, Xiao Q, Peng XY, Tang CF
Nutrients 2022 May 9;14(9)
Nutrients 2022 May 9;14(9)
Serum IL-35 levels is a new candidate biomarker of cancer-related cachexia in stage IV non-small cell lung cancer.
Li Z, Zhu L, Zheng H, Jiang W, Wang Y, Jiang Z, Xu J
Thoracic cancer 2022 Mar;13(5):716-723
Thoracic cancer 2022 Mar;13(5):716-723
Differential Protein Metabolism and Regeneration in Gastrocnemius Muscles in High-fat Diet Fed Mice and Pre-hibernation Daurian Ground Squirrels: A Comparison between Pathological and Healthy Obesity.
Yan X, Niu Q, Gao X, Shen S, He N, Wang H, Fang R, Gao Y, Chang H
Zoological studies 2021;60:e6
Zoological studies 2021;60:e6
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Zhang W, You B, Qi D, Qiu L, Ripley-Gonzalez JW, Zheng F, Fu S, Li C, Dun Y, Liu S
Scientific reports 2021 Sep 27;11(1):19116
Scientific reports 2021 Sep 27;11(1):19116
c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle.
Mori T, Ato S, Knudsen JR, Henriquez-Olguin C, Li Z, Wakabayashi K, Suginohara T, Higashida K, Tamura Y, Nakazato K, Jensen TE, Ogasawara R
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E551-E559
American journal of physiology. Endocrinology and metabolism 2021 Oct 1;321(4):E551-E559
Serum insulin-like growth factor binding protein 2 levels as biomarker for pancreatic ductal adenocarcinoma-associated malnutrition and muscle wasting.
Dong J, Yu J, Li Z, Gao S, Wang H, Yang S, Wu L, Lan C, Zhao T, Gao C, Liu Z, Wang X, Hao J
Journal of cachexia, sarcopenia and muscle 2021 Jun;12(3):704-716
Journal of cachexia, sarcopenia and muscle 2021 Jun;12(3):704-716
Differential protein metabolism and regeneration in hypertrophic diaphragm and atrophic gastrocnemius muscles in hibernating Daurian ground squirrels.
Yan X, Gao X, Niu Q, Peng X, Zhang J, Ma X, Wei Y, Wang H, Gao Y, Chang H
Experimental physiology 2021 Apr;106(4):958-971
Experimental physiology 2021 Apr;106(4):958-971
Cyanidin-3-O-glucoside inhibits epithelial-to-mesenchymal transition, and migration and invasion of breast cancer cells by upregulating KLF4.
Chen D, Yuan M, Ye Q, Wang X, Xu J, Shi G, Hu Z
Food & nutrition research 2020;64
Food & nutrition research 2020;64
Different fuel regulation in two types of myofiber results in different antioxidant strategies in Daurian ground squirrels (Spermophilus dauricus) during hibernation.
Shen-Hui X, Fu WW, Zhang J, Wang HP, Dang K, Chang H, Gao YF
The Journal of experimental biology 2020 Jan 1;
The Journal of experimental biology 2020 Jan 1;
Trichostatin A inhibits skeletal muscle atrophy induced by cigarette smoke exposure in mice.
Ding J, Li F, Cong Y, Miao J, Wu D, Liu B, Wang L
Life sciences 2019 Oct 15;235:116800
Life sciences 2019 Oct 15;235:116800
Age-dependent effects of caloric restriction on mTOR and ubiquitin-proteasome pathways in skeletal muscles.
Chen CN, Liao YH, Tsai SC, Thompson LV
GeroScience 2019 Dec;41(6):871-880
GeroScience 2019 Dec;41(6):871-880
Suppression of protein degradation by leucine requires its conversion to β-hydroxy-β-methyl butyrate in C2C12 myotubes.
Duan Y, Zhong Y, Song B, Zheng C, Xu K, Kong X, Li F
Aging 2019 Dec 24;11(24):11922-11936
Aging 2019 Dec 24;11(24):11922-11936
Beta-hydroxy beta-methyl butyrate decreases muscle protein degradation via increased Akt/FoxO3a signaling and mitochondrial biogenesis in weanling piglets after lipopolysaccharide challenge.
Duan Y, Zheng C, Zhong Y, Song B, Yan Z, Kong X, Deng J, Li F, Yin Y
Food & function 2019 Aug 1;10(8):5152-5165
Food & function 2019 Aug 1;10(8):5152-5165
3F-Box protein 32 degrades ataxia telangiectasia and Rad3-related and regulates DNA damage response induced by gemcitabine in pancreatic cancer.
Yang C, Fan P, Zhu S, Yang H, Jin X, Wu H
Oncology letters 2018 Jun;15(6):8878-8884
Oncology letters 2018 Jun;15(6):8878-8884
Spermidine-Activated Satellite Cells Are Associated with Hypoacetylation in ACVR2B and Smad3 Binding to Myogenic Genes in Mice.
Zhang L, Gong H, Sun Q, Zhao R, Jia Y
Journal of agricultural and food chemistry 2018 Jan 17;66(2):540-550
Journal of agricultural and food chemistry 2018 Jan 17;66(2):540-550
Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response.
Guo D, Wang C, Wang Q, Qiao Z, Tang H
Oncotarget 2017 Jun 13;8(24):39640-39648
Oncotarget 2017 Jun 13;8(24):39640-39648
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Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FBXO32 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FBXO32. This antibody recognizes human,mouse,rat antigen. The FBXO32 antibody has been validated for the following applications: ELISA, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 12866-1-AP( FBXO32 Antibody) at dilution of 1:600
- Other comments
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells using 12866-1-AP( FBXO32 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- Other comments
- IF
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human heart tissue slide using 12866-1-AP( FBXO32 Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC
