Antibody data
- Antibody Data
- Antigen structure
- References [110]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 21997-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- LAMP1 antibody
- Antibody type
- Polyclonal
- Description
- LAMP1 antibody (Cat. #21997-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.
Epidermal Stem Cell Derived Exosomes Alleviate Excessive Autophagy Induced Endothelial Cell Apoptosis by Delivering miR200b-3p to Diabetic Wounds.
Melanin-concentrating hormone receptor 1 is discarded by exosomes after internalization.
LAMP1 controls CXCL10-CXCR3 axis mediated inflammatory regulation of macrophage polarization during inflammatory stimulation.
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
eIF2α-mediated integrated stress response links multiple intracellular signaling pathways to reprogram vascular smooth muscle cell fate in carotid artery plaque.
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway.
Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.
Pseudorabies virus inhibits progesterone-induced inactivation of TRPML1 to facilitate viral entry.
Nuciferine protects bovine hepatocytes against free fatty acid-induced oxidative damage by activating the transcription factor EB/peroxisome proliferator-activated receptor γ coactivator 1 alpha pathway.
Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia.
Targeted Degradation of PCSK9 In Vivo by Autophagy-Tethering Compounds.
Investigation of Glycosylphosphatidylinositol (GPI)-Plasma Membrane Interaction in Live Cells and the Influence of GPI Glycan Structure on the Interaction.
Molecular basis for the different PCV2 susceptibility of T-lymphoblasts in Landrace and Piétrain pigs.
Lonicerin promotes wound healing in diabetic rats by enhancing blood vessel regeneration through Sirt1-mediated autophagy.
The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics.
Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren's disease.
Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease.
Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide-induced inhibition of malignant growth in hepatocellular carcinoma cells.
Astrocytic AT1R deficiency ameliorates Aβ-induced cognitive deficits and synaptotoxicity through β-arrestin2 signaling.
Targeted Degradation of Alpha-Synuclein by Autophagosome-Anchoring Chimera Peptides.
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
Cuproptosis-immunotherapy using PD-1 overexpressing T cell membrane-coated nanosheets efficiently treats tumor.
Functional of tongue sole (Cynoglossus semilaevis) gamma-interferon-inducible lysosomal thiol reductase with implications in innate immune reponse depend on CXXC active site.
Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis.
Ethyl Gallate Inhibits Bovine Viral Diarrhea Virus by Promoting IFITM3 Expression, Lysosomal Acidification and Protease Activity.
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Dual targets of lethal apoptosis and protective autophagy in liver cancer with periplocymarin elicit a limited therapeutic effect.
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Canine distemper virus N protein induces autophagy to facilitate viral replication.
Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates.
Complex metabolic disharmony in PMM2-CDG paves the way to new therapeutic approaches.
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H(+)-driven lysosomal pyridoxine exporter.
Capsaicin alleviates cisplatin-induced muscle loss and atrophy in vitro and in vivo.
Mitophagy bridges DNA sensing with metabolic adaption to expand lung cancer stem-like cells.
PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle.
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
LAMP3 transfer via extracellular particles induces apoptosis in Sjögren's disease.
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice.
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
PRKX down-regulates TAK1/IRF7 signaling in the antiviral innate immunity of black carp Mylopharyngodon piceus.
TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication.
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Thioredoxin interacting protein protects mice from fasting induced liver steatosis by activating ER stress and its downstream signaling pathways.
Compensatory engulfment and Müller glia reactivity in the absence of microglia.
LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization.
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation.
Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
GRN-/- iPSC-derived cortical neurons recapitulate the pathological findings of both frontotemporal lobar degeneration and neuronal ceroidolipofuscinosis.
Multi-omics analysis unravels dysregulated lysosomal function and lipid metabolism involved in sub-chronic particulate matter-induced pulmonary injury.
The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Molecular Characterization of AMPA-Receptor-Containing Vesicles.
Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer.
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice.
Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.
Circ_0030998 promotes tumor proliferation and angiogenesis by sponging miR-567 to regulate VEGFA in colorectal cancer.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy.
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Identification of Compound CB-2 as a Novel Late-Stage Autophagy Inhibitor Exhibits Inhibitory Potency against A549 Cells.
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells.
Meg3 Induces EMT and Invasion of Glioma Cells via Autophagy.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
The N-glycosylation of Equine Tetherin Affects Antiviral Activity by Regulating Its Subcellular Localization.
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Dysregulated autophagy as a new aspect of the molecular pathogenesis of Krabbe disease.
Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells.
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Identification and functional characterization of interferon-γ-inducible lysosomal thiol reductase (GILT) gene in common Chinese cuttlefish Sepiella japonica.
Circular RNA profiling provides insights into their subcellular distribution and molecular characteristics in HepG2 cells.
Sufentanil impairs autophagic degradation and inhibits cell migration in NCI-H460 in vitro.
Novel half-sandwich iridium OˆC (carbene)-Complexes: In vitro and in vivo tumor growth suppression and pro-apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes.
Acetyl-CoA Synthetase 2 Promotes Cell Migration and Invasion of Renal Cell Carcinoma by Upregulating Lysosomal-Associated Membrane Protein 1 Expression.
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.
Differential signaling pathways are initiated in macrophages during infection depending on the intracellular fate of Chlamydia spp.
LIN28A inhibits lysosome‑associated membrane glycoprotein 1 protein expression in embryonic stem and bladder cancer cells.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Molecular and biological characterization of gamma-interferon-inducible lysosomal thiol reductase in silver carp (Hypophthalmichthys molitrix).
Entosis Acts as a Novel Way within Sertoli Cells to Eliminate Spermatozoa in Seminiferous Tubule.
Upregulation of the lncRNA Meg3 induces autophagy to inhibit tumorigenesis and progression of epithelial ovarian carcinoma by regulating activity of ATG3.
Altered expression of lysosomal associated membrane protein 1 in esophageal squamous cell carcinoma.
Identification and characterization of an endoplasmic reticulum localization motif.
Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).
Chen Y, Shen J, Yuan M, Li H, Li Y, Zheng S, Han B, Zhang C, Liu S, Sun Q, Wu J
Journal of advanced research 2025 Jan;67:331-348
Journal of advanced research 2025 Jan;67:331-348
Epidermal Stem Cell Derived Exosomes Alleviate Excessive Autophagy Induced Endothelial Cell Apoptosis by Delivering miR200b-3p to Diabetic Wounds.
Xu H, Yang H, Wang Z, Tang Q, Cao X, Chen C, Dong Y, Xu Z, Lv D, Rong Y, Chen M, Tang B, Deng W, Zhu J, Hu Z
The Journal of investigative dermatology 2024 May;144(5):1134-1147.e2
The Journal of investigative dermatology 2024 May;144(5):1134-1147.e2
Melanin-concentrating hormone receptor 1 is discarded by exosomes after internalization.
Yamada R, Michimae M, Hamamoto A, Takemori H
Biochemical and biophysical research communications 2024 May 28;710:149917
Biochemical and biophysical research communications 2024 May 28;710:149917
LAMP1 controls CXCL10-CXCR3 axis mediated inflammatory regulation of macrophage polarization during inflammatory stimulation.
Ye Y, Li L, Kang H, Wan Z, Zhang M, Gang B, Liu J, Liu G, Gu W
International immunopharmacology 2024 May 10;132:111929
International immunopharmacology 2024 May 10;132:111929
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
Zheng N, Liu S, Chen J, Xu Y, Cao W, Lin J, Lu G, Zhang G
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
eIF2α-mediated integrated stress response links multiple intracellular signaling pathways to reprogram vascular smooth muscle cell fate in carotid artery plaque.
Luo J, Zhang X, Li W, Wang T, Cui S, Li T, Wang Y, Xu W, Ma Y, Yang B, Luo Y, Yang G, Xu R, Jiao L
Heliyon 2024 Mar 15;10(5):e26904
Heliyon 2024 Mar 15;10(5):e26904
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway.
Yao W, Zhang Q, Zhao Y, Xu X, Zhang S, Wang X
Journal of ethnopharmacology 2024 Mar 1;321:117536
Journal of ethnopharmacology 2024 Mar 1;321:117536
Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.
Hou Y, Chu X, Park JH, Zhu Q, Hussain M, Li Z, Madsen HB, Yang B, Wei Y, Wang Y, Fang EF, Croteau DL, Bohr VA
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):4212-4233
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):4212-4233
Pseudorabies virus inhibits progesterone-induced inactivation of TRPML1 to facilitate viral entry.
Su BQ, Yang GY, Wang J, Ming SL, Chu BB
PLoS pathogens 2024 Jan;20(1):e1011956
PLoS pathogens 2024 Jan;20(1):e1011956
Nuciferine protects bovine hepatocytes against free fatty acid-induced oxidative damage by activating the transcription factor EB/peroxisome proliferator-activated receptor γ coactivator 1 alpha pathway.
Fang Z, Jiang X, Wang S, Tai W, Jiang Q, Loor JJ, Yu H, Hao X, Chen M, Shao Q, Song Y, Lei L, Liu G, Du X, Li X
Journal of dairy science 2024 Jan;107(1):625-640
Journal of dairy science 2024 Jan;107(1):625-640
Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia.
Jiang X, Huang K, Sun X, Li Y, Hua L, Liu F, Huang R, Du J, Zeng H
iScience 2024 Jan 19;27(1):108691
iScience 2024 Jan 19;27(1):108691
Targeted Degradation of PCSK9 In Vivo by Autophagy-Tethering Compounds.
Ouyang Z, Ma M, Zhang Z, Wu H, Xue Y, Jian Y, Yin K, Yu S, Zhao C, Guo W, Gu X
Journal of medicinal chemistry 2024 Jan 11;67(1):433-449
Journal of medicinal chemistry 2024 Jan 11;67(1):433-449
Investigation of Glycosylphosphatidylinositol (GPI)-Plasma Membrane Interaction in Live Cells and the Influence of GPI Glycan Structure on the Interaction.
Kundu S, Jaiswal M, Babu Mullapudi V, Guo J, Kamat M, Basso KB, Guo Z
Chemistry (Weinheim an der Bergstrasse, Germany) 2024 Feb 7;30(8):e202303047
Chemistry (Weinheim an der Bergstrasse, Germany) 2024 Feb 7;30(8):e202303047
Molecular basis for the different PCV2 susceptibility of T-lymphoblasts in Landrace and Piétrain pigs.
Ouyang Y, Nauwynck HJ
Veterinary research 2024 Feb 19;55(1):22
Veterinary research 2024 Feb 19;55(1):22
Lonicerin promotes wound healing in diabetic rats by enhancing blood vessel regeneration through Sirt1-mediated autophagy.
Lin Z, Li LY, Chen L, Jin C, Li Y, Yang L, Li CZ, Qi CY, Gan YY, Zhang JR, Wang P, Ni LB, Wang GF
Acta pharmacologica Sinica 2024 Apr;45(4):815-830
Acta pharmacologica Sinica 2024 Apr;45(4):815-830
The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics.
Pileggi CA, Parmar G, Elkhatib H, Stewart CM, Alecu I, Côté M, Bennett SAL, Sandhu JK, Cuperlovic-Culf M, Harper ME
Current research in neurobiology 2023;5:100112
Current research in neurobiology 2023;5:100112
Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren's disease.
Nakamura H, Tanaka T, Ji Y, Zheng C, Afione SA, Warner BM, Oliveira FR, Motta ACF, Rocha EM, Noguchi M, Atsumi T, Chiorini JA
PloS one 2023;18(2):e0282227
PloS one 2023;18(2):e0282227
Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease.
Nakamura H, Tanaka T, Zheng C, Afione SA, Warner BM, Noguchi M, Atsumi T, Chiorini JA
Arthritis & rheumatology (Hoboken, N.J.) 2023 Sep;75(9):1586-1598
Arthritis & rheumatology (Hoboken, N.J.) 2023 Sep;75(9):1586-1598
Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide-induced inhibition of malignant growth in hepatocellular carcinoma cells.
Yu H, Hao Z, Liu X, Wei Z, Tan R, Liu X, Chen Q, Chen Y, Zhou H, Liu Y, Fu Z
Environmental toxicology 2023 Sep;38(9):2100-2110
Environmental toxicology 2023 Sep;38(9):2100-2110
Astrocytic AT1R deficiency ameliorates Aβ-induced cognitive deficits and synaptotoxicity through β-arrestin2 signaling.
Chen X, Gao R, Song Y, Xu T, Jin L, Zhang W, Chen Z, Wang H, Wu W, Zhang S, Zhang G, Zhang N, Chang L, Liu H, Li H, Wu Y
Progress in neurobiology 2023 Sep;228:102489
Progress in neurobiology 2023 Sep;228:102489
Targeted Degradation of Alpha-Synuclein by Autophagosome-Anchoring Chimera Peptides.
Tong Y, Zhu W, Chen J, Zhang W, Xu F, Pang J
Journal of medicinal chemistry 2023 Sep 14;66(17):12614-12628
Journal of medicinal chemistry 2023 Sep 14;66(17):12614-12628
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
Liu J, Huang Z, Yin S, Zhou X, Jiang Y, Shao L
The Science of the total environment 2023 Sep 1;889:164078
The Science of the total environment 2023 Sep 1;889:164078
Cuproptosis-immunotherapy using PD-1 overexpressing T cell membrane-coated nanosheets efficiently treats tumor.
Liu T, Zhou Z, Zhang M, Lang P, Li J, Liu Z, Zhang Z, Li L, Zhang L
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:502-512
Journal of controlled release : official journal of the Controlled Release Society 2023 Oct;362:502-512
Functional of tongue sole (Cynoglossus semilaevis) gamma-interferon-inducible lysosomal thiol reductase with implications in innate immune reponse depend on CXXC active site.
Liu M, Tao M, Li J, Sang M, Wu X, Luo H, Zhang J
Developmental and comparative immunology 2023 Oct;147:104901
Developmental and comparative immunology 2023 Oct;147:104901
Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis.
Zhang JJ, Song CG, Wang M, Zhang GQ, Wang B, Chen X, Lin P, Zhu YM, Sun ZC, Wang YZ, Jiang JL, Li L, Yang XM, Chen ZN
Journal of pharmaceutical analysis 2023 Oct;13(10):1135-1152
Journal of pharmaceutical analysis 2023 Oct;13(10):1135-1152
Ethyl Gallate Inhibits Bovine Viral Diarrhea Virus by Promoting IFITM3 Expression, Lysosomal Acidification and Protease Activity.
Zhang L, Yang G, Wang J, Zhang J, Chen K, Xiong X, Zhu Y, Xu C, Wang J
International journal of molecular sciences 2023 May 12;24(10)
International journal of molecular sciences 2023 May 12;24(10)
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Meng Z, Gao M, Wang C, Guan S, Zhang D, Lu J
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Dual targets of lethal apoptosis and protective autophagy in liver cancer with periplocymarin elicit a limited therapeutic effect.
Hao Y, Song T, Wang M, Li T, Zhao C, Li T, Hou Y, He H
International journal of oncology 2023 Mar;62(3)
International journal of oncology 2023 Mar;62(3)
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Pei X, Liu D, Li J, Li L, Ding X, Zhang W, Li Z, Xu G, Li C, Li D
The Science of the total environment 2023 Mar 20;865:161242
The Science of the total environment 2023 Mar 20;865:161242
Canine distemper virus N protein induces autophagy to facilitate viral replication.
Chen F, Guo Z, Zhang R, Zhang Z, Hu B, Bai L, Zhao S, Wu Y, Zhang Z, Li Y
BMC veterinary research 2023 Mar 15;19(1):60
BMC veterinary research 2023 Mar 15;19(1):60
Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates.
Tong Y, Zhu W, Chen J, Wen T, Xu F, Pang J
Journal of medicinal chemistry 2023 Jun 22;66(12):7926-7942
Journal of medicinal chemistry 2023 Jun 22;66(12):7926-7942
Complex metabolic disharmony in PMM2-CDG paves the way to new therapeutic approaches.
Himmelreich N, Kikul F, Zdrazilova L, Honzik T, Hecker A, Poschet G, Lüchtenborg C, Brügger B, Strahl S, Bürger F, Okun JG, Hansikova H, Thiel C
Molecular genetics and metabolism 2023 Jul;139(3):107610
Molecular genetics and metabolism 2023 Jul;139(3):107610
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
Gou Q, Che S, Chen M, Chen H, Shi J, Hou Y
Cancer science 2023 Jul;114(7):2871-2881
Cancer science 2023 Jul;114(7):2871-2881
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
Jia X, Qian J, Chen H, Liu Q, Hussain S, Jin J, Shi J, Hou Y
European journal of pharmacology 2023 Jul 5;950:175749
European journal of pharmacology 2023 Jul 5;950:175749
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
Wang Y, Chen YY, Gao GB, Zheng YH, Yu NN, Ouyang L, Gao X, Li N, Wen SY, Huang S, Zhao Q, Liu L, Cao M, Zhang S, Zhang J, He QY
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jul 5;31(7):2169-2187
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Jul 5;31(7):2169-2187
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H(+)-driven lysosomal pyridoxine exporter.
Akino S, Yasujima T, Yamashiro T, Yuasa H
Life science alliance 2023 Feb;6(2)
Life science alliance 2023 Feb;6(2)
Capsaicin alleviates cisplatin-induced muscle loss and atrophy in vitro and in vivo.
Huang KC, Chiang YF, Huang TC, Chen HY, Lin PH, Ali M, Hsia SM
Journal of cachexia, sarcopenia and muscle 2023 Feb;14(1):182-197
Journal of cachexia, sarcopenia and muscle 2023 Feb;14(1):182-197
Mitophagy bridges DNA sensing with metabolic adaption to expand lung cancer stem-like cells.
Liu Z, Shan S, Yuan Z, Wu F, Zheng M, Wang Y, Gui J, Xu W, Wang C, Ren T, Wen Z
EMBO reports 2023 Feb 6;24(2):e54006
EMBO reports 2023 Feb 6;24(2):e54006
PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle.
Hara M, Wu W, Malechka VV, Takahashi Y, Ma JX, Moiseyev G
Cell reports 2023 Feb 28;42(2):112091
Cell reports 2023 Feb 28;42(2):112091
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Liu Z, Fan M, Hou J, Pan S, Xu Y, Zhang H, Liu C, Hao X, Li X, Wang H
Cell death & disease 2023 Feb 20;14(2):144
Cell death & disease 2023 Feb 20;14(2):144
LAMP3 transfer via extracellular particles induces apoptosis in Sjögren's disease.
Tanaka T, Nakamura H, Tran DT, Warner BM, Wang Y, Atsumi T, Noguchi M, Chiorini JA
Scientific reports 2023 Feb 14;13(1):2595
Scientific reports 2023 Feb 14;13(1):2595
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Lin Y, Shi Q, Yang G, Shi F, Zhou Y, Wang T, Xu P, Li P, Liu Z, Sun H, Zhao Z, Ding K, Wang Z, Feng H, Yu B, Fang P, Wang J
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 14;120(7):e2213670120
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 14;120(7):e2213670120
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Han C, Li Z, Liu R, Zhao Z, Wang Y, Zuo X, Zhang Y, Geng Z, Huang H, Pan X, Li W
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
Gou Q, Chen H, Chen M, Shi J, Jin J, Liu Q, Hou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice.
Sun HJ, Tan JX, Shan XD, Wang ZC, Wu ZY, Bian JS, Nie XW
Metabolism: clinical and experimental 2023 Aug;145:155579
Metabolism: clinical and experimental 2023 Aug;145:155579
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
PRKX down-regulates TAK1/IRF7 signaling in the antiviral innate immunity of black carp Mylopharyngodon piceus.
Yang X, Ai Y, Chen L, Wang C, Liu J, Zhang J, Li J, Wu H, Xiao J, Chang M, Feng H
Frontiers in immunology 2022;13:999219
Frontiers in immunology 2022;13:999219
TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication.
Yan F, Yang W, Wang X, Gao G
Journal of virology 2022 Sep 14;96(17):e0091922
Journal of virology 2022 Sep 14;96(17):e0091922
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Wang J, Yang G, Zhang L, Zhang J, Wang J, Zou Y, Wang J
Virus research 2022 Nov;321:198905
Virus research 2022 Nov;321:198905
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
Liu J, Li D, Dun Y, Li H, Ripley-Gonzalez JW, Zhang J, Qiu L, You B, Liu S
Life sciences 2022 Nov 1;308:120949
Life sciences 2022 Nov 1;308:120949
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2022 Mar;37(3):549-563
Environmental toxicology 2022 Mar;37(3):549-563
Thioredoxin interacting protein protects mice from fasting induced liver steatosis by activating ER stress and its downstream signaling pathways.
Miyahara H, Hasegawa K, Yashiro M, Ohara T, Fujisawa M, Yoshimura T, Matsukawa A, Tsukahara H
Scientific reports 2022 Mar 21;12(1):4819
Scientific reports 2022 Mar 21;12(1):4819
Compensatory engulfment and Müller glia reactivity in the absence of microglia.
Thiel WA, Blume ZI, Mitchell DM
Glia 2022 Jul;70(7):1402-1425
Glia 2022 Jul;70(7):1402-1425
LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization.
Tanaka T, Warner BM, Michael DG, Nakamura H, Odani T, Yin H, Atsumi T, Noguchi M, Chiorini JA
Autophagy 2022 Jul;18(7):1629-1647
Autophagy 2022 Jul;18(7):1629-1647
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Ma C, Wu H, Yang G, Xiang J, Feng K, Zhang J, Hua Y, Kang L, Fan G, Yang S
British journal of pharmacology 2022 Jan;179(2):252-269
British journal of pharmacology 2022 Jan;179(2):252-269
A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation.
Aring L, Choi EK, Kopera H, Lanigan T, Iwase S, Klionsky DJ, Seo YA
Journal of neurochemistry 2022 Feb;160(3):356-375
Journal of neurochemistry 2022 Feb;160(3):356-375
Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
Kang Y, Yin S, Liu J, Jiang Y, Huang Z, Chen L, Shao L
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
GRN-/- iPSC-derived cortical neurons recapitulate the pathological findings of both frontotemporal lobar degeneration and neuronal ceroidolipofuscinosis.
Bossolasco P, Cimini S, Maderna E, Bardelli D, Canafoglia L, Cavallaro T, Ricci M, Silani V, Marucci G, Rossi G
Neurobiology of disease 2022 Dec;175:105891
Neurobiology of disease 2022 Dec;175:105891
Multi-omics analysis unravels dysregulated lysosomal function and lipid metabolism involved in sub-chronic particulate matter-induced pulmonary injury.
Yan L, Chen S, Hou C, Lin J, Xiong W, Shen Y, Zhou T
The Science of the total environment 2022 Aug 25;836:155642
The Science of the total environment 2022 Aug 25;836:155642
The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.
Zhang G, Han J, Wang L, Yang X, Yan Z, Qu M, Zhou H, Bilal H, Wang F, Ge H, Yang X
iScience 2022 Apr 15;25(4):104085
iScience 2022 Apr 15;25(4):104085
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Xiong Q, Li X, Li W, Chen G, Xiao H, Li P, Wu C
Frontiers in molecular biosciences 2021;8:645831
Frontiers in molecular biosciences 2021;8:645831
Molecular Characterization of AMPA-Receptor-Containing Vesicles.
Peters JJ, Leitz J, Oses-Prieto JA, Burlingame AL, Brunger AT
Frontiers in molecular neuroscience 2021;14:754631
Frontiers in molecular neuroscience 2021;14:754631
Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.
Chu BX, Li YN, Liu N, Yuan LX, Chen SY, Zhu YH, Wang JF
Frontiers in immunology 2021;12:757909
Frontiers in immunology 2021;12:757909
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
Yu P, Li Y, Zhong G, Li W, Chen B, Zhang J
Frontiers in physiology 2021;12:737474
Frontiers in physiology 2021;12:737474
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Zhu X, Zhuo Y, Wu S, Chen Y, Ye J, Deng Y, Feng Y, Liu R, Cai S, Zou Z, Wang B, Wu CL, Zeng G, Zhong W
Frontiers in oncology 2021;11:632524
Frontiers in oncology 2021;11:632524
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
International journal of molecular sciences 2021 Oct 12;22(20)
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Fan Y, Lu J, Liu J, Zhang R, Yu Z, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer.
Punturi NB, Seker S, Devarakonda V, Mazumder A, Kalra R, Chen CH, Li S, Primeau T, Ellis MJ, Kavuri SM, Haricharan S
Nature communications 2021 May 19;12(1):2940
Nature communications 2021 May 19;12(1):2940
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
Li H, Dun Y, Zhang W, You B, Liu Y, Fu S, Qiu L, Cheng J, Ripley-Gonzalez JW, Liu S
Life sciences 2021 May 15;273:119314
Life sciences 2021 May 15;273:119314
GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice.
Yuan W, Lu L, Rao M, Huang Y, Liu CE, Liu S, Zhao Y, Liu H, Zhu J, Chao T, Wu C, Ren J, Lv L, Li W, Qi S, Liang Y, Yue S, Gao J, Zhang Z, Kong E
Proceedings of the National Academy of Sciences of the United States of America 2021 Mar 30;118(13)
Proceedings of the National Academy of Sciences of the United States of America 2021 Mar 30;118(13)
Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.
Isogawa K, Asano M, Hayazaki M, Koga K, Watanabe M, Suzuki K, Kobayashi T, Kawaguchi K, Ishizuka A, Kato S, Ito H, Hamamoto A, Koyama H, Furuta K, Takemori H
Journal of cellular biochemistry 2021 Jun;122(6):667-678
Journal of cellular biochemistry 2021 Jun;122(6):667-678
Circ_0030998 promotes tumor proliferation and angiogenesis by sponging miR-567 to regulate VEGFA in colorectal cancer.
Jin L, Han C, Zhai T, Zhang X, Chen C, Lian L
Cell death discovery 2021 Jun 24;7(1):160
Cell death discovery 2021 Jun 24;7(1):160
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
Wu H, Feng K, Zhang C, Zhang H, Zhang J, Hua Y, Dong Z, Zhu Y, Yang S, Ma C
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
Zou L, Zhang X, Xiong M, Meng L, Tian Y, Pan L, Yuan X, Chen G, Wang Z, Bu L, Yao Z, Zhang Z, Ye K, Zhang Z
Neurobiology of disease 2021 Jul;154:105326
Neurobiology of disease 2021 Jul;154:105326
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy.
Wang R, Zhu Y, Ren C, Yang S, Tian S, Chen H, Jin M, Zhou H
Autophagy 2021 Feb;17(2):496-511
Autophagy 2021 Feb;17(2):496-511
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Zhang Z, Mou Z, Xu C, Wu S, Dai X, Chen X, Ou Y, Chen Y, Yang C, Jiang H
Cell death & disease 2021 Aug 7;12(8):778
Cell death & disease 2021 Aug 7;12(8):778
Identification of Compound CB-2 as a Novel Late-Stage Autophagy Inhibitor Exhibits Inhibitory Potency against A549 Cells.
Liu Z, Zhang L, Liu Y, Zhang H, Chen J, Feng G, Yang P, Sha F, Cui L, Sun G
Life (Basel, Switzerland) 2021 Aug 23;11(8)
Life (Basel, Switzerland) 2021 Aug 23;11(8)
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
Lu J, Fan Y, Liu M, Zhang Q, Guan S
Toxicology 2021 Apr 30;454:152716
Toxicology 2021 Apr 30;454:152716
Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells.
Ko EJ, Ock MS, Choi YH, Iovanna JL, Mun S, Han K, Kim HS, Cha HJ
International journal of molecular sciences 2021 Apr 11;22(8)
International journal of molecular sciences 2021 Apr 11;22(8)
Meg3 Induces EMT and Invasion of Glioma Cells via Autophagy.
Yang Z, Bian E, Xu Y, Ji X, Tang F, Ma C, Wang H, Zhao B
OncoTargets and therapy 2020;13:989-1000
OncoTargets and therapy 2020;13:989-1000
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.
Mao K, Chen J, Yu H, Li H, Ren Y, Wu X, Wen Y, Zou F, Li W
Aging cell 2020 Jun;19(6):e13163
Aging cell 2020 Jun;19(6):e13163
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, Zhang HT, Gao X, Liu L
Aging 2020 Jun 27;12(13):13297-13317
Aging 2020 Jun 27;12(13):13297-13317
mTORC1-dependent TFEB nucleus translocation and pro-survival autophagy induced by zeolitic imidazolate framework-8.
Ding H, Song Y, Huang X, Wang L, Luo S, Zhang H, Pan H, Jiang W, Qian J, Yao G, Wen L, Zhang Y
Biomaterials science 2020 Jul 28;8(15):4358-4369
Biomaterials science 2020 Jul 28;8(15):4358-4369
The N-glycosylation of Equine Tetherin Affects Antiviral Activity by Regulating Its Subcellular Localization.
Bai B, Wang XF, Zhang M, Na L, Zhang X, Zhang H, Yang Z, Wang X
Viruses 2020 Feb 16;12(2)
Viruses 2020 Feb 16;12(2)
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
Wu X, Sun R, Wang H, Yang B, Wang F, Xu H, Chen S, Zhao R, Pi J, Xu Y
Oxidative medicine and cellular longevity 2019;2019:1038932
Oxidative medicine and cellular longevity 2019;2019:1038932
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, Huo Z, Xu G
PloS one 2019;14(8):e0221104
PloS one 2019;14(8):e0221104
Dysregulated autophagy as a new aspect of the molecular pathogenesis of Krabbe disease.
Del Grosso A, Angella L, Tonazzini I, Moscardini A, Giordano N, Caleo M, Rocchiccioli S, Cecchini M
Neurobiology of disease 2019 Sep;129:195-207
Neurobiology of disease 2019 Sep;129:195-207
Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells.
Jiang C, Jiang L, Li Q, Liu X, Zhang T, Yang G, Zhang C, Wang N, Sun X, Jiang L
Toxicology 2019 Sep 1;425:152238
Toxicology 2019 Sep 1;425:152238
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Sheng J, Shen L, Sun L, Zhang X, Cui R, Wang L
Cell proliferation 2019 May;52(3):e12609
Cell proliferation 2019 May;52(3):e12609
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Dong H, Hussain Mangi M, Ni J, Yang L, Zhou X
Cells 2019 May 26;8(5)
Cells 2019 May 26;8(5)
Identification and functional characterization of interferon-γ-inducible lysosomal thiol reductase (GILT) gene in common Chinese cuttlefish Sepiella japonica.
Pang Z, Zhang Y, Liu L
Fish & shellfish immunology 2019 Mar;86:627-634
Fish & shellfish immunology 2019 Mar;86:627-634
Circular RNA profiling provides insights into their subcellular distribution and molecular characteristics in HepG2 cells.
Zhang J, Zhang X, Li C, Yue L, Ding N, Riordan T, Yang L, Li Y, Jen C, Lin S, Zhou D, Chen F
RNA biology 2019 Feb;16(2):220-232
RNA biology 2019 Feb;16(2):220-232
Sufentanil impairs autophagic degradation and inhibits cell migration in NCI-H460 in vitro.
Jiang H, Wang H, Zou W, Hu Y, Chen C, Wang C
Oncology letters 2019 Dec;18(6):6829-6835
Oncology letters 2019 Dec;18(6):6829-6835
Novel half-sandwich iridium OˆC (carbene)-Complexes: In vitro and in vivo tumor growth suppression and pro-apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes.
Xu Z, Zhang Y, Zhang S, Jia X, Zhong G, Yang Y, Du Q, Li J, Liu Z
Cancer letters 2019 Apr 10;447:75-85
Cancer letters 2019 Apr 10;447:75-85
Acetyl-CoA Synthetase 2 Promotes Cell Migration and Invasion of Renal Cell Carcinoma by Upregulating Lysosomal-Associated Membrane Protein 1 Expression.
Yao L, Guo X, Gui Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(3):984-992
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(3):984-992
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, Li W
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.
Deng M, Tang Y, Li W, Wang X, Zhang R, Zhang X, Zhao X, Liu J, Tang C, Liu Z, Huang Y, Peng H, Xiao L, Tang D, Scott MJ, Wang Q, Liu J, Xiao X, Watkins S, Li J, Yang H, Wang H, Chen F, Tracey KJ, Billiar TR, Lu B
Immunity 2018 Oct 16;49(4):740-753.e7
Immunity 2018 Oct 16;49(4):740-753.e7
Differential signaling pathways are initiated in macrophages during infection depending on the intracellular fate of Chlamydia spp.
Nagarajan UM, Tripathy M, Kollipara A, Allen J 4th, Goodwin A, Whittimore J, Wyrick PB, Rank RG
Immunology and cell biology 2018 Mar;96(3):246-256
Immunology and cell biology 2018 Mar;96(3):246-256
LIN28A inhibits lysosome‑associated membrane glycoprotein 1 protein expression in embryonic stem and bladder cancer cells.
Pan P, Chen T, Zhang Y, Qi Z, Qin J, Cui G, Guo X
Molecular medicine reports 2018 Jul;18(1):399-406
Molecular medicine reports 2018 Jul;18(1):399-406
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, Zhao M, He H, Zhang Y, Rao Q, Zhao D, Wang Y, Fan L, Li P, Liu Y, Liu F, Zhang F, Ye J, Yan Q, Guo S, Wang Z
Scientific reports 2018 Jul 2;8(1):9972
Scientific reports 2018 Jul 2;8(1):9972
Molecular and biological characterization of gamma-interferon-inducible lysosomal thiol reductase in silver carp (Hypophthalmichthys molitrix).
Cao F, Wu H, Lv T, Yang Y, Li Y, Liu S, Hu L, Xu X, Ma L, Zhang X, Li J, Bi X, Gu W, Zhang S
Fish & shellfish immunology 2018 Aug;79:73-78
Fish & shellfish immunology 2018 Aug;79:73-78
Entosis Acts as a Novel Way within Sertoli Cells to Eliminate Spermatozoa in Seminiferous Tubule.
Ahmed N, Yang P, Huang Y, Chen H, Liu T, Wang L, Nabi F, Liu Y, Chen Q
Frontiers in physiology 2017;8:361
Frontiers in physiology 2017;8:361
Upregulation of the lncRNA Meg3 induces autophagy to inhibit tumorigenesis and progression of epithelial ovarian carcinoma by regulating activity of ATG3.
Xiu YL, Sun KX, Chen X, Chen S, Zhao Y, Guo QG, Zong ZH
Oncotarget 2017 May 9;8(19):31714-31725
Oncotarget 2017 May 9;8(19):31714-31725
Altered expression of lysosomal associated membrane protein 1 in esophageal squamous cell carcinoma.
Huang J, Li L, Liu J, Yu J, Wu X, Xu Y, Ma M, Wang W, Zhang R
Pathology, research and practice 2017 Aug;213(8):938-942
Pathology, research and practice 2017 Aug;213(8):938-942
Identification and characterization of an endoplasmic reticulum localization motif.
Nie YW, Wang M, Zhang P, Huan L, Liu DJ
Biochemical and biophysical research communications 2016 Apr 22;473(1):249-254
Biochemical and biophysical research communications 2016 Apr 22;473(1):249-254
Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).
Zhou N, Pan T, Zhang J, Li Q, Zhang X, Bai C, Huang F, Peng T, Zhang J, Liu C, Tao L, Zhang H
The Journal of biological chemistry 2016 Apr 22;291(17):9218-32
The Journal of biological chemistry 2016 Apr 22;291(17):9218-32
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- Experimental details
- RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 21997-1-AP( CD107a Antibody) at dilution of 1:2000
- Other comments
- WB