CABT-BL7995

antibody from Creative Diagnostics

Targeting: LAMP1 CD107a

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL7995

Provider

Creative Diagnostics

Product name

Anti-LAMP1 Monoclonal antibody, clone 2E5C

Antibody type

Monoclonal

Description

CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Isotype

IgG