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- Antibody Data
- Antigen structure
- References [22]
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- Validations
- Western blot [1]
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- Product number
- NB120-19294 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB120-19294, RRID:AB_2134502
- Product name
- Rabbit Polyclonal LAMP-1/CD107a Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. LAMP1 - Lysosome Marker
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- 1 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution.
BRF1 ameliorates LPS-induced inflammation through autophagy crosstalking with MAPK/ERK signaling.
Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response.
Entosis Acts as a Novel Way within Sertoli Cells to Eliminate Spermatozoa in Seminiferous Tubule.
Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.
Electro-Magnetic Nano-Particle Bound Beclin1 siRNA Crosses the Blood-Brain Barrier to Attenuate the Inflammatory Effects of HIV-1 Infection in Vitro.
TBC1D20 mediates autophagy as a key regulator of autophagosome maturation.
Amyloid-β42 protofibrils are internalized by microglia more extensively than monomers.
Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure.
The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes.
The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance.
Rapid degradation of the complement regulator, CD59, by a novel inhibitor.
Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections.
Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion.
Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.
Age-related oxidative stress compromises endosomal proteostasis.
Plasmid DNA is internalized from the apical plasma membrane of the salivary gland epithelium in live animals.
Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons.
Human immunodeficiency virus type 1 endocytic trafficking through macrophage bridging conduits facilitates spread of infection.
Macrophage endocytic trafficking of antiretroviral nanoparticles.
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Saha P, Shumate JL, Caldwell JG, Elghobashi-Meinhardt N, Lu A, Zhang L, Olsson NE, Elias JE, Pfeffer SR
eLife 2020 May 15;9
eLife 2020 May 15;9
Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution.
Kevadiya BD, Woldstad C, Ottemann BM, Dash P, Sajja BR, Lamberty B, Morsey B, Kocher T, Dutta R, Bade AN, Liu Y, Callen SE, Fox HS, Byrareddy SN, McMillan JM, Bronich TK, Edagwa BJ, Boska MD, Gendelman HE
Theranostics 2018;8(1):256-276
Theranostics 2018;8(1):256-276
BRF1 ameliorates LPS-induced inflammation through autophagy crosstalking with MAPK/ERK signaling.
Xie W, Zheng W, Liu M, Qin Q, Zhao Y, Cheng Z, Guo F
Genes & diseases 2018 Sep;5(3):226-234
Genes & diseases 2018 Sep;5(3):226-234
Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response.
Mittal E, Skowyra ML, Uwase G, Tinaztepe E, Mehra A, Köster S, Hanson PI, Philips JA
mBio 2018 Nov 27;9(6)
mBio 2018 Nov 27;9(6)
Entosis Acts as a Novel Way within Sertoli Cells to Eliminate Spermatozoa in Seminiferous Tubule.
Ahmed N, Yang P, Huang Y, Chen H, Liu T, Wang L, Nabi F, Liu Y, Chen Q
Frontiers in physiology 2017;8:361
Frontiers in physiology 2017;8:361
Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.
Köster S, Upadhyay S, Chandra P, Papavinasasundaram K, Yang G, Hassan A, Grigsby SJ, Mittal E, Park HS, Jones V, Hsu FF, Jackson M, Sassetti CM, Philips JA
Proceedings of the National Academy of Sciences of the United States of America 2017 Oct 10;114(41):E8711-E8720
Proceedings of the National Academy of Sciences of the United States of America 2017 Oct 10;114(41):E8711-E8720
Electro-Magnetic Nano-Particle Bound Beclin1 siRNA Crosses the Blood-Brain Barrier to Attenuate the Inflammatory Effects of HIV-1 Infection in Vitro.
Rodriguez M, Kaushik A, Lapierre J, Dever SM, El-Hage N, Nair M
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2017 Mar;12(1):120-132
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2017 Mar;12(1):120-132
TBC1D20 mediates autophagy as a key regulator of autophagosome maturation.
Sidjanin DJ, Park AK, Ronchetti A, Martins J, Jackson WT
Autophagy 2016 Oct 2;12(10):1759-1775
Autophagy 2016 Oct 2;12(10):1759-1775
Amyloid-β42 protofibrils are internalized by microglia more extensively than monomers.
Gouwens LK, Makoni NJ, Rogers VA, Nichols MR
Brain research 2016 Oct 1;1648(Pt A):485-495
Brain research 2016 Oct 1;1648(Pt A):485-495
Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure.
Dever SM, Rodriguez M, Lapierre J, Costin BN, El-Hage N
Frontiers in microbiology 2015;6:653
Frontiers in microbiology 2015;6:653
The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes.
Khatter D, Raina VB, Dwivedi D, Sindhwani A, Bahl S, Sharma M
Journal of cell science 2015 May 1;128(9):1746-61
Journal of cell science 2015 May 1;128(9):1746-61
The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance.
Case ED, Chong A, Wehrly TD, Hansen B, Child R, Hwang S, Virgin HW, Celli J
Cellular microbiology 2014 Jun;16(6):862-77
Cellular microbiology 2014 Jun;16(6):862-77
Rapid degradation of the complement regulator, CD59, by a novel inhibitor.
Cai B, Xie S, Liu F, Simone LC, Caplan S, Qin X, Naslavsky N
The Journal of biological chemistry 2014 Apr 25;289(17):12109-25
The Journal of biological chemistry 2014 Apr 25;289(17):12109-25
Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections.
Puligujja P, McMillan J, Kendrick L, Li T, Balkundi S, Smith N, Veerubhotla RS, Edagwa BJ, Kabanov AV, Bronich T, Gendelman HE, Liu XM
Nanomedicine : nanotechnology, biology, and medicine 2013 Nov;9(8):1263-73
Nanomedicine : nanotechnology, biology, and medicine 2013 Nov;9(8):1263-73
Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion.
Ejlerskov P, Rasmussen I, Nielsen TT, Bergström AL, Tohyama Y, Jensen PH, Vilhardt F
The Journal of biological chemistry 2013 Jun 14;288(24):17313-35
The Journal of biological chemistry 2013 Jun 14;288(24):17313-35
Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.
Scharf B, Clement CC, Wu XX, Morozova K, Zanolini D, Follenzi A, Larocca JN, Levon K, Sutterwala FS, Rand J, Cobelli N, Purdue E, Hajjar KA, Santambrogio L
Nature communications 2012 Mar 27;3:755
Nature communications 2012 Mar 27;3:755
Age-related oxidative stress compromises endosomal proteostasis.
Cannizzo ES, Clement CC, Morozova K, Valdor R, Kaushik S, Almeida LN, Follo C, Sahu R, Cuervo AM, Macian F, Santambrogio L
Cell reports 2012 Jul 26;2(1):136-49
Cell reports 2012 Jul 26;2(1):136-49
Plasmid DNA is internalized from the apical plasma membrane of the salivary gland epithelium in live animals.
Sramkova M, Masedunskas A, Weigert R
Histochemistry and cell biology 2012 Aug;138(2):201-13
Histochemistry and cell biology 2012 Aug;138(2):201-13
Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons.
Liang Q, Ouyang X, Schneider L, Zhang J
Molecular neurodegeneration 2011 Jun 1;6:37
Molecular neurodegeneration 2011 Jun 1;6:37
Human immunodeficiency virus type 1 endocytic trafficking through macrophage bridging conduits facilitates spread of infection.
Kadiu I, Gendelman HE
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2011 Dec;6(4):658-75
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2011 Dec;6(4):658-75
Macrophage endocytic trafficking of antiretroviral nanoparticles.
Kadiu I, Nowacek A, McMillan J, Gendelman HE
Nanomedicine (London, England) 2011 Aug;6(6):975-94
Nanomedicine (London, England) 2011 Aug;6(6):975-94
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Ishikawa H, Ma Z, Barber GN
Nature 2009 Oct 8;461(7265):788-92
Nature 2009 Oct 8;461(7265):788-92
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LAMP-1/CD107a Antibody [NB120-19294] - Analysis of 20 ug of HeLa cell lysate and 5 ul of Molecular Weight Protein Ladder per well.
