Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 20366-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20366-1-AP, RRID:AB_10694152
- Product name
- SUZ12 antibody
- Antibody type
- Polyclonal
- Description
- SUZ12 antibody (Cat. #20366-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance.
The Interplay Between HIF-1α and EZH2 in Lung Cancer and Dual-Targeted Drug Therapy.
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2.
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.
Mechanical force-sensitive lncRNA SNHG8 inhibits osteogenic differentiation by regulating EZH2 in hPDLSCs.
TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways.
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis.
N-terminal truncated carboxypeptidase E represses E-cadherin expression in lung cancer by stabilizing the Snail-HDAC complex.
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition.
TRPS1 Suppresses Breast Cancer Epithelial-mesenchymal Transition Program as a Negative Regulator of SUZ12.
A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.
Polycomb repressive complex 2 facilitates the nuclear export of the influenza viral genome through the interaction with M1.
Wei W, Liu K, Huang X, Tian S, Wang H, Zhang C, Ye J, Dong Y, An Z, Ma X, Wang B, Huang Y, Zhang X
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):2
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):2
The Interplay Between HIF-1α and EZH2 in Lung Cancer and Dual-Targeted Drug Therapy.
Wang J, Yang C, Xu H, Fan X, Jia L, Du Y, Liu S, Wang W, Zhang J, Zhang Y, Wang X, Liu Z, Bao J, Li S, Yang J, Wu C, Tang J, Chen G, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2303904
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2303904
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Hu W, Zhai ZY, Huang ZY, Chen ZM, Zhou P, Li XX, Yang GH, Bao CJ, You LJ, Cui XB, Xia GL, Ou Yang MP, Zhang L, Wu WKK, Li LF, Zhang YX, Xiao ZG, Gong W
mSystems 2024 Apr 16;9(4):e0020624
mSystems 2024 Apr 16;9(4):e0020624
Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2.
Su R, Cao W, Ma G, Li W, Li Z, Liu Y, Chen L, Chen Z, Li X, Cui P, Huang G
Frontiers in pharmacology 2023;14:1326245
Frontiers in pharmacology 2023;14:1326245
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.
Ghate NB, Kim S, Shin Y, Kim J, Doche M, Valena S, Situ A, Kim S, Rhie SK, Lenz HJ, Ulmer TS, Mumenthaler SM, An W
Nature communications 2023 Apr 17;14(1):2140
Nature communications 2023 Apr 17;14(1):2140
Mechanical force-sensitive lncRNA SNHG8 inhibits osteogenic differentiation by regulating EZH2 in hPDLSCs.
Zhang Z, He Q, Yang S, Zhao X, Li X, Wei F
Cellular signalling 2022 May;93:110285
Cellular signalling 2022 May;93:110285
TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways.
Tchasovnikarova IA, Marr SK, Damle M, Kingston RE
Molecular cell 2022 Jan 20;82(2):479-491.e7
Molecular cell 2022 Jan 20;82(2):479-491.e7
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
Wang C, Chen X, Liu X, Lu D, Li S, Qu L, Yin F, Luo H, Zhang Y, Luo Z, Cui N, Kong L, Wang X
European journal of medicinal chemistry 2022 Aug 5;238:114462
European journal of medicinal chemistry 2022 Aug 5;238:114462
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis.
Li Z, Wang D, Chen X, Wang W, Wang P, Hou P, Li M, Chu S, Qiao S, Zheng J, Bai J
Cell death & disease 2021 Nov 13;12(11):1080
Cell death & disease 2021 Nov 13;12(11):1080
N-terminal truncated carboxypeptidase E represses E-cadherin expression in lung cancer by stabilizing the Snail-HDAC complex.
Sun J, Meng D, Yu T, Li F, Zhang G, Tian X, Zhao N, Li G, Li L, Wang H, Liu Y, Meng Y, Ma Y, Wan Z, Bao J, Piao H
American journal of cancer research 2020;10(3):925-938
American journal of cancer research 2020;10(3):925-938
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition.
Zhang KL, Shen QQ, Fang YF, Sun YM, Ding J, Chen Y
Acta pharmacologica Sinica 2019 Dec;40(12):1587-1595
Acta pharmacologica Sinica 2019 Dec;40(12):1587-1595
TRPS1 Suppresses Breast Cancer Epithelial-mesenchymal Transition Program as a Negative Regulator of SUZ12.
Hu J, Su P, Jiao M, Bai X, Qi M, Liu H, Wu Z, Sun J, Zhou G, Han B
Translational oncology 2018 Apr;11(2):416-425
Translational oncology 2018 Apr;11(2):416-425
A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.
Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, Wan L, Zhang Z, Zhang C, Qin X, Xiao M, Ye D, Liu Y, Han Z, Wang S, Mao L, Wei W, Chen W
The EMBO journal 2017 May 2;36(9):1243-1260
The EMBO journal 2017 May 2;36(9):1243-1260
Polycomb repressive complex 2 facilitates the nuclear export of the influenza viral genome through the interaction with M1.
Asaka MN, Kawaguchi A, Sakai Y, Mori K, Nagata K
Scientific reports 2016 Sep 20;6:33608
Scientific reports 2016 Sep 20;6:33608
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 20366-1-AP(SUZ12 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SUZ12 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SUZ12. This antibody recognizes human,mouse,rat antigen. The SUZ12 antibody has been validated for the following applications: ELISA, WB, IHC analysis.