Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B12278 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human CD300E monoclonal antibody, clone VQ-I3 [FITC]
- Antibody type
- Monoclonal
- Description
- The monoclonal antibody UP-H2 reacts with human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells. CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
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