Antibody data

Product number
BS60015 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FCAR polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human FCAR
Description
Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens, such as microorganisms and pathogens, by removing Ig-coated antigen complexes from circulation. Fc receptors are present on lymphoid and myeloid derivatives, where they mediate endocytosis of Ig-antigen complexes, antibody production in B cells through T cell antigen presentation, cytotoxicity, and the release of cytokines and reactive oxygen species. Human myeloid receptor for the Fc fragment of IgA (CD89) is a glycoprotein that is expressed on the surface of neutrophils, monocytes, macrophages and eosinophils and is a potent cytotoxic trigger molecule. Cytokines can initiate a highbinding state for CD89 through a mechanism that involves the intracellular C-terminus of CD89.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FCAR protein structure - BS60015 shown in red.