66187-1-Ig

antibody from Proteintech Group

Targeting: KRT18

Provider product page for 66187-1-Ig

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ELISA

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [27]
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Validations
Western blot [1]

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Product number: 66187-1-Ig - Provider product page
Provider: Proteintech Group
Product name: Cytokeratin 18 antibody
Antibody type: Monoclonal
Description: Cytokeratin 18 antibody (Cat. #66187-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat, Porcine
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1G11C4
Vial size: 20ul, 150ul

KRT18 protein structure - 66187-1-Ig shown in red.

Submitted references ELF5 modulates casein synthesis in goat mammary epithelial cells via JAK2/STAT5 signaling pathway.

Guo Y, Ma C, Meng T, Tu T, Cui S, Ling Y, Zhang Y, Liu H, Song N
Animal bioscience 2026 Feb;39(2):250181-0

EMB is essential for enteric nervous system development mediated by PI3K signaling.

Li Z, Zhuansun D, Meng X, Yang H, Xiao J, Chen Y, Wang J, Yu X, Li Z, You J, Chen X, Feng C, Wu L, Chu X, Duan W, Wang K, Li Z, Tou J, Yu L, Tang W, Liu Y, Jiang X, Ren H, Yu M, Yin Q, Liu X, Xu Z, Wu D, Jiao C, Yu D, Wu X, Zhu T, Yang J, Xiang L, Wang J, Wang Q, Zhou B, Wang D, Chen K, Mao H, Wang B, Zhan J, Wang CY, Zeng W, Chen F, Xiong B, Feng J
Genome medicine 2025 Sep 25;17(1):102

TBRG4 regulates ubiquitination of Beclin1 and participates in autophagy pathway to inhibit intervertebral disc degeneration.

Cui X, Zhang F, Cui D, Zhang W, Wu H, Chen X, Yu H
The spine journal : official journal of the North American Spine Society 2025 Nov;25(11):2569-2584

ER stress induced extracellular vesicles secretion from macrophages promotes calcium oxalate crystals formation in kidney.

Yuan Y, Ma Y, Dai L, Jin X, Qi S, Yin Z
Molecular biomedicine 2025 Nov 17;6(1):110

Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties.

Jeppesen DK, Sanchez ZC, Kelley NM, Hayes JB, Ambroise J, Koory EN, Krystofiak E, Taneja N, Zhang Q, Dungan MM, Perkins OL, Tyska MJ, Knapik EW, Dean KM, Doran AC, Coffey RJ, Burnette DT
Nature cell biology 2025 Mar;27(3):438-448

RBM10 deficiency promotes brain metastasis by modulating sphingolipid metabolism in a BBB model of EGFR mutant lung adenocarcinoma.

Xu G, An B, Wang R, Pan B, Hao H, Ren X, Jing Z, Gao W, Li Y, Jin Y, Lin E, Shang L, Jia D, Yu Y
Journal of experimental & clinical cancer research : CR 2025 Mar 11;44(1):95

Rab8a and Vps35 influence intracellular transport of vitamin E via α-Tocopherol transport protein in hepatocytes.

Jian L, Wang B, Gao Y, Xue Y, Guan Y, Qu Y, Liu K, Yan L, Li S, Luo H
International journal of biological macromolecules 2025 Jun;311(Pt 3):143021

CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.

Liu M, Gong Y, Cai H, Hua R, Li H, Wang Z, Zhou Y, Ma Y, Quan S
Journal of translational medicine 2025 Jul 10;23(1):763

New idea of Fuke Qianjin capsule in treating sequelae of pelvic inflammatory disease: Anti-inflammatory in the early stage and reparative in the later stage.

Xu C, Yi M, Xiao Z, Xiang F, Wu M, Zhang Z, Zheng Y, Gong Y, Li Y, Su L, Liao Y, Zhang P, Xia B, Liao D, Lin L
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119066

Crosstalk Signaling Between the Epithelial and Non-Epithelial Compartments of the Mouse Inner Ear.

David AP, Biswas S, Soltis MP, Eltawil Y, Zhou R, Easow SA, Cheng AG, Heller S, Jan TA
Journal of the Association for Research in Otolaryngology : JARO 2025 Apr;26(2):127-145

Identifying differentially expressed genes in goat mammary epithelial cells induced by overexpression of SOCS3 gene using RNA sequencing.

Song N, Ma C, Guo Y, Cui S, Chen S, Chen Z, Ling Y, Zhang Y, Liu H
Frontiers in veterinary science 2024;11:1392152

Overexpression of wild-type HRAS drives non-alcoholic steatohepatitis to hepatocellular carcinoma in mice.

Ling C, Liu SS, Wang YY, Huo GT, Yang YW, Xu N, Wang H, Wu Y, Miao YF, Fu R, Zhao YW, Fan CF
Zoological research 2024 May 18;45(3):551-566

MiR-135a-5p regulates window of implantation by suppressing pinopodes development and decidualization of endometrial stromal cells.

He Y, Ju Y, Lei H, Dong J, Jin N, Lu J, Chen S, Wang X
Journal of assisted reproduction and genetics 2024 Jun;41(6):1645-1659

Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA.

Zhang M, Hussain A, Hu B, Yang H, Li C, Guo S, Han X, Li B, Dai Y, Cao Y, Chi H, Weng Y, Qin CF, Huang Y
Nature communications 2024 Jul 31;15(1):6463

MiRNA-26a-5p inhibits preterm labor initiation by targeting and regulating TRPC3 ion channel protein expression.

Chen J, Liu T, Cui H, Na Q, Liu S
Environmental toxicology 2024 Jan;39(1):357-366

Menstrual blood-derived mesenchymal stem cells combining with platelet-rich plasma infusion in endometrium repair.

Wang Y, Liu W, Xu H, Dong L, Jiao Y, Qiao Z
The journal of obstetrics and gynaecology research 2024 Dec;50(12):2338-2345

Distribution of Monocarboxylate Transporters in Brain and Choroid Plexus Epithelium.

Ueno M, Chiba Y, Murakami R, Miyai Y, Matsumoto K, Wakamatsu K, Takebayashi G, Uemura N, Yanase K
Pharmaceutics 2023 Jul 31;15(8)

Nicotinamide N-Methyltransferase Remodeled Cell Metabolism and Aggravated Proinflammatory Responses by Activating STAT3/IL1β/PGE(2) Pathway.

Yang C, Wang T, Zhu S, Zong Z, Luo C, Zhao Y, Liu J, Li T, Liu X, Liu C, Deng H
ACS omega 2022 Oct 25;7(42):37509-37519

ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury.

Wang Y, Zhang M, Bi R, Su Y, Quan F, Lin Y, Yue C, Cui X, Zhao Q, Liu S, Yang Y, Zhang D, Cao Q, Gao X
Redox biology 2022 May;51:102262

CRISPR/Cas9-Induced Knockout of miR-24 Reduces Cholesterol and Monounsaturated Fatty Acid Content in Primary Goat Mammary Epithelial Cells.

Huang L, Luo J, Gao W, Song N, Tian H, Zhu L, Jiang Q, Loor JJ
Foods (Basel, Switzerland) 2022 Jul 7;11(14)

Expansion of mouse castration-resistant intermediate prostate stem cells in vitro.

Xu Y, Mu J, Zhou Z, Leng Y, Yu Y, Song X, Liu A, Zhu H, Li J, Wang D
Stem cell research & therapy 2022 Jul 15;13(1):299

Mutation of Signal Transducer and Activator of Transcription 5 (STAT5) Binding Sites Decreases Milk Allergen α(S1)-Casein Content in Goat Mammary Epithelial Cells.

Song N, Luo J, Huang L, Zang S, He Q, Wu J, Huang J
Foods (Basel, Switzerland) 2022 Jan 26;11(3)

High-Contrast Luminescent Immunohistochemistry Using PEGylated Lanthanide Complexes.

Su F, Luo X, Du Z, Chen Z, Liu Y, Jin X, Guo Z, Lu J, Jin D
Analytical chemistry 2022 Dec 20;94(50):17587-17594

Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2.

Liu Q, Pang J, Wang LA, Huang Z, Xu J, Yang X, Xie Q, Huang Y, Tang T, Tong D, Liu G, Wang L, Zhang D, Ma Q, Xiao H, Lan W, Qin J, Jiang J
The Journal of pathology 2021 Jan;253(1):106-118

T-cadherin inhibits invasion and migration of endometrial stromal cells in endometriosis.

Lu Q, Huang Y, Wu J, Guan Y, Du M, Wang F, Liu Z, Zhu Y, Gong G, Hou H, Zhang M, Zhang JY, Ning F, Chen L, Wang L, Lash GE
Human reproduction (Oxford, England) 2020 Jan 1;35(1):145-156

Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer.

Dong B, Miao J, Wang Y, Luo W, Ji Z, Lai H, Zhang M, Cheng X, Wang J, Fang Y, Zhu HH, Chua CW, Fan L, Zhu Y, Pan J, Wang J, Xue W, Gao WQ
Communications biology 2020 Dec 16;3(1):778

Carbon monoxide inhibits the nuclear-cytoplasmic translocation of HMGB1 in an in vitro oxidative stress injury model of mouse renal tubular epithelial cells.

Jia Y, Wang L, Zhao GY, Wang ZQ, Chen S, Chen G
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2016 Dec;36(6):791-795

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The KRT18 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human KRT18. This antibody recognizes human antigen. The KRT18 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 66187-1-Ig.pdf

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