53-9815-82

antibody from Invitrogen Antibodies
Targeting: KRT18
Provider product page for 53-9815-82
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
53-9815-82 - Provider product page
Provider
Invitrogen Antibodies
Product name
Cytokeratin 18 Monoclonal Antibody (LDK18), Alexa Fluor™ 488, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The monoclonal antibody LDK18 recognizes human Cytokeratin 18. Cytokeratin 18 is member of the large family of intermediate filaments found within epithelial cells. The family of cytokeratins is made up of type I (acidic) and type II (basic) members which form heterodimers by pairing an acidic with a basic member to compose the keratin filament. Cytokeratin 18 (type I) is most commonly found associated with cytokeratin 8 (type II). Because many tumors of epithelial origin retain expression of keratin proteins, cytokeratin 18 has been used as a tumor marker to identify both tumors and metastases. In addition, cytokeratin 18 has been shown to be expressed in highly proliferative retinal pigment epithelium cells. Applications Reported: This LDK18 antibody has been reported for use in microscopy, immunohistochemical staining, and immunocytochemistry. Applications Tested: This LDK18 antibody has been tested by immunocytochemistry of MeOH-fixed human cells and can be used at less than or equal to 5 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Antibody clone number
LDK18
Vial size
100 µg
Concentration
0.5 mg/mL
Storage
4° C, store in dark, DO NOT FREEZE!
KRT18 protein structure - 53-9815-82 shown in red.