Ab098863

antibody from Aladdin Scientific
Targeting: KRT18
Provider product page for Ab098863
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
Ab098863 - Provider product page
Provider
Aladdin Scientific
Product name
Recombinant Cytokeratin 18 Antibody
Antibody type
Recombinant
Description
Rabbit anti HumanÊCytokeratin 18 Antibody,ÊPrimary antibody,Êcould be used forÊWB, IHC, Flow, IF/ICC, IP and so on.ApplicationWB:Ê1/2000 - 1/5000 Ê ÊÊIHC: 1/800 - 1/1600Flow: 1/800 - 1/2000IF/ICC:Ê1/800 - 1/2000IP:Ê 1/25FunctionInvolved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.Post-translationalPhosphorylation at Ser-34 increases during mitosis. Hyperphosphorylated at Ser-53 in diseased cirrhosis liver. Phosphorylation increases by IL-6. Proteolytically cleaved by caspases during epithelial cell apoptosis. Cleavage occurs at Asp-238 by either caspase-3, caspase-6 or caspase-7. O-glycosylated at multiple sites; glycans consist of single N-acetylglucosamine residues.
Reactivity
Human, Rat
Host
Rabbit
Conjugate
Unconjugated
Antibody clone number
RR693
Vial size
100_l,10_l,1ml,50_l
Concentration
0,5 mg/ml
Storage
Store at -20¡C for 2 years. Upon delivery aliquot. Avoid freeze/thaw cycle.
KRT18 protein structure - Ab098863 shown in red.